Non-Syndromic Cleft Lip with or without Cleft Palate: Genome-Wide Association Study in Europeans Identifies a Suggestive Risk Locus at 16p12.1 and Supports SH3PXD2A as a Clefting Susceptibility Gene

Iris A. L. M. van Rooij, Kerstin U. Ludwig, Julia Welzenbach, Nina Ishorst, Michelle Thonissen, Tessel E. Galesloot, Edwin Ongkosuwito, Stefaan J. Berge, Khalid Aldhorae, Augusto Rojas-Martinez, Lambertus A. L. M. Kiemeney, Joris Robert Vermeesch, Han Brunner, Nel Roeleveld, Koen Devriendt, Titiaan Dormaar, Greet Hens, Michael Knapp, Carine Carels, Elisabeth Mangold*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1023
Number of pages14
JournalGenes
Volume10
Issue number12
DOIs
Publication statusPublished - 7 Dec 2019

Keywords

  • congenital malformation
  • orofacial cleft
  • cleft lip with or without cleft palate
  • genome-wide association study
  • NONSYNDROMIC OROFACIAL CLEFTS
  • GENOTYPE IMPUTATION
  • CANDIDATE GENES
  • VARIANTS
  • IRF6
  • METAANALYSES
  • FOXE1

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