Non-Syndromic Cleft Lip with or without Cleft Palate: Genome-Wide Association Study in Europeans Identifies a Suggestive Risk Locus at 16p12.1 and Supports SH3PXD2A as a Clefting Susceptibility Gene

Iris A. L. M. van Rooij, Kerstin U. Ludwig, Julia Welzenbach, Nina Ishorst, Michelle Thonissen, Tessel E. Galesloot, Edwin Ongkosuwito, Stefaan J. Berge, Khalid Aldhorae, Augusto Rojas-Martinez, Lambertus A. L. M. Kiemeney, Joris Robert Vermeesch, Han Brunner, Nel Roeleveld, Koen Devriendt, Titiaan Dormaar, Greet Hens, Michael Knapp, Carine Carels, Elisabeth Mangold*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1023
Number of pages14
JournalGenes
Volume10
Issue number12
DOIs
Publication statusPublished - 7 Dec 2019

Keywords

  • congenital malformation
  • orofacial cleft
  • cleft lip with or without cleft palate
  • genome-wide association study
  • NONSYNDROMIC OROFACIAL CLEFTS
  • GENOTYPE IMPUTATION
  • CANDIDATE GENES
  • VARIANTS
  • IRF6
  • METAANALYSES
  • FOXE1

Cite this

van Rooij, I. A. L. M., Ludwig, K. U., Welzenbach, J., Ishorst, N., Thonissen, M., Galesloot, T. E., Ongkosuwito, E., Berge, S. J., Aldhorae, K., Rojas-Martinez, A., Kiemeney, L. A. L. M., Vermeesch, J. R., Brunner, H., Roeleveld, N., Devriendt, K., Dormaar, T., Hens, G., Knapp, M., Carels, C., & Mangold, E. (2019). Non-Syndromic Cleft Lip with or without Cleft Palate: Genome-Wide Association Study in Europeans Identifies a Suggestive Risk Locus at 16p12.1 and Supports SH3PXD2A as a Clefting Susceptibility Gene. Genes, 10(12), [1023]. https://doi.org/10.3390/genes10121023