Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease

Raquel Figuinha Videira, Paula A. da Costa Martins, Ines Falcao-Pires*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Web of Science)

Abstract

In 2020, cardiovascular diseases (CVDs) remain a leading cause of mortality and morbidity, contributing to the burden of the already overloaded health system. Late or incorrect diagnosis of patients with CVDs compromises treatment efficiency and patient's outcome. Diagnosis of CVDs could be facilitated by detection of blood-based biomarkers that reliably reflect the current condition of the heart. In the last decade, non-coding RNAs (ncRNAs) present on human biofluids including serum, plasma, and blood have been reported as potential biomarkers for CVDs. This paper reviews recent studies that focus on the use of ncRNAs as biomarkers of CVDs.

Original languageEnglish
Article number9285
Number of pages20
JournalInternational journal of molecular sciences
Volume21
Issue number23
DOIs
Publication statusPublished - Dec 2020

Keywords

  • ncRNAs
  • biomarkers
  • cardiovascular diseases
  • diagnosis
  • NONINVASIVE BIOMARKERS
  • MYOCARDIAL-INFARCTION
  • CORONARY ATHEROSCLEROSIS
  • PRENATAL DETECTION
  • PROGNOSTIC VALUE
  • HEART-FAILURE
  • CIRCULAR RNAS
  • PLASMA
  • DIAGNOSIS
  • MICRORNAS

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