Abstract
The aim of this study was to investigate the effect of trans alpha -linolenic acid on platelet aggregation and blood haemostasis. A randomized, double blind dietary intervention trial was carried out with healthy male volunteers (n=88) in three European centers. After a 6-week washout period where subjects avoided foods containing all trans fats, subjects either continued for 6 weeks with a low trans diet or a diet where trans alpha -linolenic acid provided 0.6% of energy (supplied as oil, margarine, cheese, muffins, and biscuits). At the end of the washout period the intake of trans polyunsaturated fats was 58+/-115 mg/day; this increased in patients on the high trans diet by +1344+/-328 mg/day, compared with +10+/-67 mg/day in patients on the low trans diet (p
Original language | English |
---|---|
Pages (from-to) | 133-141 |
Number of pages | 8 |
Journal | Thrombosis Research |
Volume | 100 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jan 2000 |