No Effect of Acute and 6-Day Nitrate Supplementation on VO2 and Time-Trial Performance in Highly Trained Cyclists

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Abstract

While the majority of studies reporting ergogenic effects of dietary nitrate have used a multiday supplementation protocol, some studies suggest that a single dose of dietary nitrate before exercise can also improve subsequent perfonuance. We aimed to compare the impact of acute and 6-day sodium nitrate supplementation on oxygen uptake (Vover dotO(2)) and time-trial performance in trained cyclists. Using a randomized, double-blind, cross-over design, 17 male cyclists (25 +/- 4 y, Vover dotO(2peak) 65 +/- 4 ml.kg(-1).min(-1), W-max 411 +/- 35 W) were subjected to 3 different trials; 5 days placebo and 1 day sodium nitrate supplementation (1-DAY); 6 days sodium nitrate supplementation (6-DAY); 6 days placebo supplementation (PLA). Nitrate was administered as 1097 mg sodium nitrate providing 800 mg (similar to 12.9 mmol) nitrate per day. Three hours after ingestion of the last supplemental bolus, indirect calorimetry was performed while subjects performed 30 min of exercise at 45% W-max and 30 min at 65% W-max on a cycle ergometer, followed by a 10 km time-trial. Immediately before exercise, plasma [nitrate] and [nitrite] increased to a similar extent during the 6-DAY and 1-DAY trial, but not with PLA (plasma nitrite: 501 +/- 205, 553 +/- 278, and 239 +/- 74 nM, respectively; p

Original languageEnglish
Pages (from-to)11-17
Number of pages7
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume27
Issue number1
DOIs
Publication statusPublished - Feb 2017

Keywords

  • nitrite
  • ergogenic aid
  • sodium nitrate
  • DIETARY NITRATE
  • BEETROOT JUICE
  • ENDURANCE PERFORMANCE
  • EXERCISE
  • HUMANS
  • SINGLE
  • MUSCLE
  • COST

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