Abstract
Plant-derived proteins have been suggested to have less anabolic properties when compared with animal-derived proteins. Whether blends of plant- and animal-derived proteins can compensate for their lesser anabolic potential has not been assessed. The present study compares post-prandial muscle protein synthesis rates following the ingestion of milk protein with wheat protein or a blend of wheat plus milk protein in healthy, young males. In a randomised, double-blind, parallel-group design, 36 males (23 (sd 3) years) received a primed continuous L-[ring-C-13(6)]-phenylalanine infusion after which they ingested 30 g milk protein (MILK), 30 g wheat protein (WHEAT) or a 30 g blend combining 15 g wheat plus 15 g milk protein (WHEAT+MILK). Blood and muscle biopsies were collected frequently for 5 h to assess post-prandial plasma amino acid profiles and subsequent myofibrillar protein synthesis rates. Ingestion of protein increased myofibrillar protein synthesis rates in all treatments (P < 0 center dot 001). Post-prandial myofibrillar protein synthesis rates did not differ between MILK v. WHEAT (0 center dot 053 (sd 0 center dot 013) v. 0 center dot 056 (sd 0 center dot 012) %center dot h(-1), respectively; t test P = 0 center dot 56) or between MILK v. WHEAT+MILK (0 center dot 053 (sd 0 center dot 013) v. 0 center dot 059 (sd 0 center dot 025) %center dot h(-1), respectively; t test P = 0 center dot 46). In conclusion, ingestion of 30 g milk protein, 30 g wheat protein or a blend of 15 g wheat plus 15 g milk protein increases muscle protein synthesis rates in young males. Furthermore, muscle protein synthesis rates following the ingestion of 30 g milk protein do not differ from rates observed after ingesting 30 g wheat protein or a blend with 15 g milk plus 15 g wheat protein in healthy, young males.
Original language | English |
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Article number | 0007114521000635 |
Pages (from-to) | 1832-1842 |
Number of pages | 11 |
Journal | British Journal of Nutrition |
Volume | 126 |
Issue number | 12 |
DOIs | |
Publication status | Published - 28 Dec 2021 |
Keywords
- Muscle protein synthesis
- Plant-based proteins
- Dairy
- Protein blends
- Fractional synthesis rate
- Young healthy males
- RESISTANCE EXERCISE
- SKELETAL-MUSCLE
- IN-VIVO
- OLDER
- LEUCINE
- REST
- STIMULATION
- ANABOLISM
- CASEIN
- BIOPSY