Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient

Samuel Heuts*, Johannes F. Ubben, Vanessa Banks-Gonzales, Jan-Willem Sels, Roberto Lorusso, Walther N. K. A. van Mook, Thijs S. R. Delnoij

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Patients with coronavirus disease 2019 (COVID-19) are prone to pulmonary artery hypertension (PAH) and right ventricular pressure overload due to severe bilateral infiltrates, high ventilation pressures, persistent hypoxemia, pulmonary fibrosis, and/or pulmonary embolism. In patients on extracorporeal membrane oxygenation (ECMO), this potentially leads to increased recirculation. In the current report, the authors present a case in which continuous inhaled nitric oxide (iNO)-enriched ventilation was effective in terms of PAH and recirculation reduction in a COVID-19 patient on veno-venous ECMO. (C) 2020 The Authors. Published by Elsevier Inc.

Original languageEnglish
Pages (from-to)2763-2767
Number of pages5
JournalJournal of Cardiothoracic and Vascular Anesthesia
Issue number9
Publication statusPublished - Sept 2021


  • COVID-19
  • acute respiratory distress syndrome
  • extracorporeal membrane oxygenation
  • inhaled nitric oxide

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