Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response

Sara Zafarnia; Jessica Bzyl-Ibach; Igor Spivak; Yongping Li; Susanne Koletnik; Dennis Doleschel; Anne Rix; Sibylle Pochon; Isabelle Tardy; Seena Koyadan; Marc van Zandvoort; Moritz Palmowski; Fabian Kiessling; Wiltrud Lederle

doi:10.1016/j.neo.2017.08.009

Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response

Sara Zafarnia, Jessica Bzyl-Ibach, Igor Spivak, Yongping Li, Susanne Koletnik, Dennis Doleschel, Anne Rix, Sibylle Pochon, Isabelle Tardy, Seena Koyadan, Marc van Zandvoort, Moritz Palmowski, Fabian Kiessling, Wiltrud Lederle^*

^*Corresponding author for this work

G&C - Moleculaire Celbiologie

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	896-907
Number of pages	12
Journal	Neoplasia (Online)
Volume	19
Issue number	11
DOIs	https://doi.org/10.1016/j.neo.2017.08.009
Publication status	Published - Nov 2017

Keywords

ENDOTHELIAL GROWTH-FACTOR
SQUAMOUS-CELL CARCINOMA
VEGFR2-TARGETED MICROBUBBLES
PERICYTE COVERAGE
CONTRAST AGENT
MOLECULAR US
PDGF-B
THERAPY
EXPRESSION
METASTASIS

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10.1016/j.neo.2017.08.009

Cite this

Zafarnia, S., Bzyl-Ibach, J., Spivak, I., Li, Y., Koletnik, S., Doleschel, D., Rix, A., Pochon, S., Tardy, I., Koyadan, S., van Zandvoort, M., Palmowski, M., Kiessling, F., & Lederle, W. (2017). Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response. Neoplasia (Online), 19(11), 896-907. https://doi.org/10.1016/j.neo.2017.08.009

Zafarnia, Sara ; Bzyl-Ibach, Jessica ; Spivak, Igor ; Li, Yongping ; Koletnik, Susanne ; Doleschel, Dennis ; Rix, Anne ; Pochon, Sibylle ; Tardy, Isabelle ; Koyadan, Seena ; van Zandvoort, Marc ; Palmowski, Moritz ; Kiessling, Fabian ; Lederle, Wiltrud. / Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response. In: Neoplasia (Online). 2017 ; Vol. 19, No. 11. pp. 896-907.

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title = "Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response",

keywords = "ENDOTHELIAL GROWTH-FACTOR, SQUAMOUS-CELL CARCINOMA, VEGFR2-TARGETED MICROBUBBLES, PERICYTE COVERAGE, CONTRAST AGENT, MOLECULAR US, PDGF-B, THERAPY, EXPRESSION, METASTASIS",

author = "Sara Zafarnia and Jessica Bzyl-Ibach and Igor Spivak and Yongping Li and Susanne Koletnik and Dennis Doleschel and Anne Rix and Sibylle Pochon and Isabelle Tardy and Seena Koyadan and {van Zandvoort}, Marc and Moritz Palmowski and Fabian Kiessling and Wiltrud Lederle",

year = "2017",

month = nov,

doi = "10.1016/j.neo.2017.08.009",

language = "English",

volume = "19",

pages = "896--907",

journal = "Neoplasia (Online)",

issn = "1476-5586",

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Zafarnia, S, Bzyl-Ibach, J, Spivak, I, Li, Y, Koletnik, S, Doleschel, D, Rix, A, Pochon, S, Tardy, I, Koyadan, S, van Zandvoort, M, Palmowski, M, Kiessling, F & Lederle, W 2017, 'Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response', Neoplasia (Online), vol. 19, no. 11, pp. 896-907. https://doi.org/10.1016/j.neo.2017.08.009

Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response. / Zafarnia, Sara; Bzyl-Ibach, Jessica; Spivak, Igor; Li, Yongping; Koletnik, Susanne; Doleschel, Dennis; Rix, Anne; Pochon, Sibylle; Tardy, Isabelle; Koyadan, Seena; van Zandvoort, Marc; Palmowski, Moritz; Kiessling, Fabian; Lederle, Wiltrud.

In: Neoplasia (Online), Vol. 19, No. 11, 11.2017, p. 896-907.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response

AU - Zafarnia, Sara

AU - Bzyl-Ibach, Jessica

AU - Spivak, Igor

AU - Li, Yongping

AU - Koletnik, Susanne

AU - Doleschel, Dennis

AU - Rix, Anne

AU - Pochon, Sibylle

AU - Tardy, Isabelle

AU - Koyadan, Seena

AU - van Zandvoort, Marc

AU - Palmowski, Moritz

AU - Kiessling, Fabian

AU - Lederle, Wiltrud

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KW - SQUAMOUS-CELL CARCINOMA

KW - VEGFR2-TARGETED MICROBUBBLES

KW - PERICYTE COVERAGE

KW - CONTRAST AGENT

KW - MOLECULAR US

KW - PDGF-B

KW - THERAPY

KW - EXPRESSION

KW - METASTASIS

U2 - 10.1016/j.neo.2017.08.009

DO - 10.1016/j.neo.2017.08.009

M3 - Article

VL - 19

SP - 896

EP - 907

JO - Neoplasia (Online)

JF - Neoplasia (Online)

SN - 1476-5586

IS - 11

ER -