Next-Generation Sequencing: An Emerging Tool for Drug Designing

Background: With the outbreak of high throughput next-generation sequencing (NGS), the biological research of drug discovery has been directed towards the oncology and infectious disease therapeutic areas, with extensive use in biopharmaceutical development and vaccine production.

Method: In this review, an effort was made to address the basic background or NGS technologies, potential applications of NGS in drug designing. Our purpose is also to provide a brief introduction of various Next-generation sequencing techniques.

Discussions: The high-throughput methods execute Large-scale Unbiased Sequencing (LUS) which comprises of Massively Parallel Sequencing (MPS) or NGS technologies. The Next gene involved necessarily executes Large-scale Unbiased Sequencing (LUS) which comprises of MPS or NGS technologies. These are related terms that describe a DNA sequencing technology which has revolutionized genomic research. Using NGS, an entire human genome can be sequenced within a single day.

Conclusion: Analysis of NGS data unravels important clues in the quest for the treatment of various life threatening diseases and other related scientific problems related to human welfare.