Neutrophil Gelatinase-associated Lipocalin as a Biomarker for Predicting Acute Kidney Injury during Off-pump Coronary Artery Bypass Grafting

Muralidhar Kanchi; R. Manjunath; Jos Massen; Lloyd Vincent; Kumar Belani

doi:10.4103/aca.ACA_48_17

Neutrophil Gelatinase-associated Lipocalin as a Biomarker for Predicting Acute Kidney Injury during Off-pump Coronary Artery Bypass Grafting

Muralidhar Kanchi^*
, R. Manjunath
, Jos Massen
, Lloyd Vincent
, Kumar Belani

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: Acute kidney injury (AKI) following cardiac surgery is a major complication resulting in increased morbidity, mortality, and economic burden. In this study, we assessed the usefulness of estimating serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in predicting AKI in patients with stable chronic kidney disease (CKD) and undergoing off-pump coronary artery bypass grafting (OP-CABG). Patients and Methods: We prospectively studied sixty nondialysis-dependent CKD patients with estimated glomerular filtration rate

Original language	English
Pages (from-to)	297-302
Number of pages	6
Journal	Annals of Cardiac Anaesthesia
Volume	20
Issue number	3
DOIs	https://doi.org/10.4103/aca.ACA_48_17
Publication status	Published - 2017

Keywords

Acute kidney injury
cardiac surgery
coronary artery bypass grafting
creatinine
dopamine
neutrophil gelatinase-associated lipocalin
ADULT CARDIAC-SURGERY
RENAL DYSFUNCTION
SEPTIC SHOCK
URINARY BIOMARKERS
DOPAMINE
NGAL
REVASCULARIZATION
NOREPINEPHRINE
METAANALYSIS
HNL/NGAL

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title = "Neutrophil Gelatinase-associated Lipocalin as a Biomarker for Predicting Acute Kidney Injury during Off-pump Coronary Artery Bypass Grafting",

abstract = "Background: Acute kidney injury (AKI) following cardiac surgery is a major complication resulting in increased morbidity, mortality, and economic burden. In this study, we assessed the usefulness of estimating serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in predicting AKI in patients with stable chronic kidney disease (CKD) and undergoing off-pump coronary artery bypass grafting (OP-CABG). Patients and Methods: We prospectively studied sixty nondialysis-dependent CKD patients with estimated glomerular filtration rate",

keywords = "Acute kidney injury, cardiac surgery, coronary artery bypass grafting, creatinine, dopamine, neutrophil gelatinase-associated lipocalin, ADULT CARDIAC-SURGERY, RENAL DYSFUNCTION, SEPTIC SHOCK, URINARY BIOMARKERS, DOPAMINE, NGAL, REVASCULARIZATION, NOREPINEPHRINE, METAANALYSIS, HNL/NGAL",

author = "Muralidhar Kanchi and R. Manjunath and Jos Massen and Lloyd Vincent and Kumar Belani",

year = "2017",

doi = "10.4103/aca.ACA\_48\_17",

language = "English",

volume = "20",

pages = "297--302",

journal = "Annals of Cardiac Anaesthesia",

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TY - JOUR

T1 - Neutrophil Gelatinase-associated Lipocalin as a Biomarker for Predicting Acute Kidney Injury during Off-pump Coronary Artery Bypass Grafting

AU - Kanchi, Muralidhar

AU - Manjunath, R.

AU - Massen, Jos

AU - Vincent, Lloyd

AU - Belani, Kumar

PY - 2017

Y1 - 2017

N2 - Background: Acute kidney injury (AKI) following cardiac surgery is a major complication resulting in increased morbidity, mortality, and economic burden. In this study, we assessed the usefulness of estimating serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in predicting AKI in patients with stable chronic kidney disease (CKD) and undergoing off-pump coronary artery bypass grafting (OP-CABG). Patients and Methods: We prospectively studied sixty nondialysis-dependent CKD patients with estimated glomerular filtration rate

AB - Background: Acute kidney injury (AKI) following cardiac surgery is a major complication resulting in increased morbidity, mortality, and economic burden. In this study, we assessed the usefulness of estimating serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in predicting AKI in patients with stable chronic kidney disease (CKD) and undergoing off-pump coronary artery bypass grafting (OP-CABG). Patients and Methods: We prospectively studied sixty nondialysis-dependent CKD patients with estimated glomerular filtration rate

KW - Acute kidney injury

KW - cardiac surgery

KW - coronary artery bypass grafting

KW - creatinine

KW - dopamine

KW - neutrophil gelatinase-associated lipocalin

KW - ADULT CARDIAC-SURGERY

KW - RENAL DYSFUNCTION

KW - SEPTIC SHOCK

KW - URINARY BIOMARKERS

KW - DOPAMINE

KW - NGAL

KW - REVASCULARIZATION

KW - NOREPINEPHRINE

KW - METAANALYSIS

KW - HNL/NGAL

U2 - 10.4103/aca.ACA_48_17

DO - 10.4103/aca.ACA_48_17

M3 - Article

C2 - 28701593

SN - 0971-9784

VL - 20

SP - 297

EP - 302

JO - Annals of Cardiac Anaesthesia

JF - Annals of Cardiac Anaesthesia

IS - 3

ER -

Neutrophil Gelatinase-associated Lipocalin as a Biomarker for Predicting Acute Kidney Injury during Off-pump Coronary Artery Bypass Grafting

Abstract

Keywords

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