TY - JOUR
T1 - Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review
AU - Andrade, Pablo
AU - Noblesse, Lieke H. M.
AU - Temel, Yasin
AU - Ackermans, Linda
AU - Lim, Lee W.
AU - Steinbusch, Harry W. M.
AU - Visser-Vandewalle, Veerle
PY - 2010/4
Y1 - 2010/4
N2 - Major depressive disorder is one of the most disabling and common diagnoses amongst psychiatric disorders, with a current worldwide prevalence of 5-10% of the general population and up to 20-25% for the lifetime period. Nowadays, conventional treatment includes psychotherapy and pharmacotherapy; however, more than 60% of the treated patients respond unsatisfactorily, and almost one fifth becomes refractory to these therapies at long-term follow-up. Growing social incapacity and economic burdens make the medical community strive for better therapies, with fewer complications. Various nonpharmacological techniques like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation, lesion surgery, and deep brain stimulation have been developed for this purpose. We reviewed the literature from the beginning of the twentieth century until July 2009 and described the early clinical effects and main reported complications of these methods.
AB - Major depressive disorder is one of the most disabling and common diagnoses amongst psychiatric disorders, with a current worldwide prevalence of 5-10% of the general population and up to 20-25% for the lifetime period. Nowadays, conventional treatment includes psychotherapy and pharmacotherapy; however, more than 60% of the treated patients respond unsatisfactorily, and almost one fifth becomes refractory to these therapies at long-term follow-up. Growing social incapacity and economic burdens make the medical community strive for better therapies, with fewer complications. Various nonpharmacological techniques like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation, lesion surgery, and deep brain stimulation have been developed for this purpose. We reviewed the literature from the beginning of the twentieth century until July 2009 and described the early clinical effects and main reported complications of these methods.
KW - Major depressive disorder
KW - Electroconvulsive therapy
KW - Vagus nerve stimulation
KW - Transcranial magnetic stimulation
KW - Psychosurgery
KW - Deep brain stimulation
U2 - 10.1007/s00701-009-0589-6
DO - 10.1007/s00701-009-0589-6
M3 - Article
C2 - 20101419
SN - 0001-6268
VL - 152
SP - 565
EP - 577
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
IS - 4
ER -