Network integration and modelling of dynamic drug responses at multi-omics levels

Nathalie Selevsek; Florian Caiment; Ramona Nudischer; Hans Gmuender; Irina Agarkova; Francis L. Atkinson; Ivo Bachmann; Vanessa Baier; Gal Barel; Chris Bauer; Stefan Boerno; Nicolas Bosc; Olivia Clayton; Henrik Cordes; Sally Deeb; Stefano Gotta; Patrick Guye; Anne Hersey; Fiona M. I. Hunter; Laura Kunz; Alex Lewalle; Matthias Lienhard; Jort Merken; Jasmine Minguet; Bernardo Oliveira; Carla Pluess; Ugis Sarkans; Yannick Schrooders; Johannes Schuchhardt; Ines Smit; Christoph Thiel; Bernd Timmermann; Marcha Verheijen; Timo Wittenberger; Witold Wolski; Alexandra Zerck; Stephane Heymans; Lars Kuepfer; Adrian Roth; Ralph Schlapbach; Steven Niederer; Ralf Herwig; Jos Kleinjans

doi:10.1038/s42003-020-01302-8

Network integration and modelling of dynamic drug responses at multi-omics levels

Nathalie Selevsek, Florian Caiment, Ramona Nudischer, Hans Gmuender, Irina Agarkova, Francis L. Atkinson, Ivo Bachmann, Vanessa Baier, Gal Barel, Chris Bauer, Stefan Boerno, Nicolas Bosc, Olivia Clayton, Henrik Cordes, Sally Deeb, Stefano Gotta, Patrick Guye, Anne Hersey, Fiona M. I. Hunter, Laura KunzAlex Lewalle, Matthias Lienhard, Jort Merken, Jasmine Minguet, Bernardo Oliveira, Carla Pluess, Ugis Sarkans, Yannick Schrooders, Johannes Schuchhardt, Ines Smit, Christoph Thiel, Bernd Timmermann, Marcha Verheijen, Timo Wittenberger, Witold Wolski, Alexandra Zerck, Stephane Heymans, Lars Kuepfer, Adrian Roth, Ralph Schlapbach, Steven Niederer, Ralf Herwig^*, Jos Kleinjans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	573
Number of pages	15
Journal	Communications Biology
Volume	3
Issue number	1
DOIs	https://doi.org/10.1038/s42003-020-01302-8
Publication status	Published - 15 Oct 2020

Keywords

INDUCED HEART-FAILURE
GENE-EXPRESSION
BIOCONDUCTOR PACKAGE
CLINICAL-PRACTICE
CARDIOTOXICITY
DOXORUBICIN
SEQ
CARDIOMYOPATHY
MECHANISMS
TOXICITY

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Cite this

Selevsek, N., Caiment, F., Nudischer, R., Gmuender, H., Agarkova, I., Atkinson, F. L., Bachmann, I., Baier, V., Barel, G., Bauer, C., Boerno, S., Bosc, N., Clayton, O., Cordes, H., Deeb, S., Gotta, S., Guye, P., Hersey, A., Hunter, F. M. I., ... Kleinjans, J. (2020). Network integration and modelling of dynamic drug responses at multi-omics levels. Communications Biology, 3(1), [573]. https://doi.org/10.1038/s42003-020-01302-8

Selevsek, Nathalie ; Caiment, Florian ; Nudischer, Ramona ; Gmuender, Hans ; Agarkova, Irina ; Atkinson, Francis L. ; Bachmann, Ivo ; Baier, Vanessa ; Barel, Gal ; Bauer, Chris ; Boerno, Stefan ; Bosc, Nicolas ; Clayton, Olivia ; Cordes, Henrik ; Deeb, Sally ; Gotta, Stefano ; Guye, Patrick ; Hersey, Anne ; Hunter, Fiona M. I. ; Kunz, Laura ; Lewalle, Alex ; Lienhard, Matthias ; Merken, Jort ; Minguet, Jasmine ; Oliveira, Bernardo ; Pluess, Carla ; Sarkans, Ugis ; Schrooders, Yannick ; Schuchhardt, Johannes ; Smit, Ines ; Thiel, Christoph ; Timmermann, Bernd ; Verheijen, Marcha ; Wittenberger, Timo ; Wolski, Witold ; Zerck, Alexandra ; Heymans, Stephane ; Kuepfer, Lars ; Roth, Adrian ; Schlapbach, Ralph ; Niederer, Steven ; Herwig, Ralf ; Kleinjans, Jos. / Network integration and modelling of dynamic drug responses at multi-omics levels. In: Communications Biology. 2020 ; Vol. 3, No. 1.

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title = "Network integration and modelling of dynamic drug responses at multi-omics levels",

keywords = "INDUCED HEART-FAILURE, GENE-EXPRESSION, BIOCONDUCTOR PACKAGE, CLINICAL-PRACTICE, CARDIOTOXICITY, DOXORUBICIN, SEQ, CARDIOMYOPATHY, MECHANISMS, TOXICITY",

author = "Nathalie Selevsek and Florian Caiment and Ramona Nudischer and Hans Gmuender and Irina Agarkova and Atkinson, {Francis L.} and Ivo Bachmann and Vanessa Baier and Gal Barel and Chris Bauer and Stefan Boerno and Nicolas Bosc and Olivia Clayton and Henrik Cordes and Sally Deeb and Stefano Gotta and Patrick Guye and Anne Hersey and Hunter, {Fiona M. I.} and Laura Kunz and Alex Lewalle and Matthias Lienhard and Jort Merken and Jasmine Minguet and Bernardo Oliveira and Carla Pluess and Ugis Sarkans and Yannick Schrooders and Johannes Schuchhardt and Ines Smit and Christoph Thiel and Bernd Timmermann and Marcha Verheijen and Timo Wittenberger and Witold Wolski and Alexandra Zerck and Stephane Heymans and Lars Kuepfer and Adrian Roth and Ralph Schlapbach and Steven Niederer and Ralf Herwig and Jos Kleinjans",

year = "2020",

month = oct,

day = "15",

doi = "10.1038/s42003-020-01302-8",

language = "English",

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journal = "Communications Biology",

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Selevsek, N, Caiment, F, Nudischer, R, Gmuender, H, Agarkova, I, Atkinson, FL, Bachmann, I, Baier, V, Barel, G, Bauer, C, Boerno, S, Bosc, N, Clayton, O, Cordes, H, Deeb, S, Gotta, S, Guye, P, Hersey, A, Hunter, FMI, Kunz, L, Lewalle, A, Lienhard, M, Merken, J, Minguet, J, Oliveira, B, Pluess, C, Sarkans, U, Schrooders, Y, Schuchhardt, J, Smit, I, Thiel, C, Timmermann, B, Verheijen, M, Wittenberger, T, Wolski, W, Zerck, A, Heymans, S, Kuepfer, L, Roth, A, Schlapbach, R, Niederer, S, Herwig, R & Kleinjans, J 2020, 'Network integration and modelling of dynamic drug responses at multi-omics levels', Communications Biology, vol. 3, no. 1, 573. https://doi.org/10.1038/s42003-020-01302-8

Network integration and modelling of dynamic drug responses at multi-omics levels. / Selevsek, Nathalie; Caiment, Florian; Nudischer, Ramona; Gmuender, Hans; Agarkova, Irina; Atkinson, Francis L.; Bachmann, Ivo; Baier, Vanessa; Barel, Gal; Bauer, Chris; Boerno, Stefan; Bosc, Nicolas; Clayton, Olivia; Cordes, Henrik; Deeb, Sally; Gotta, Stefano; Guye, Patrick; Hersey, Anne; Hunter, Fiona M. I.; Kunz, Laura; Lewalle, Alex; Lienhard, Matthias; Merken, Jort; Minguet, Jasmine; Oliveira, Bernardo; Pluess, Carla; Sarkans, Ugis; Schrooders, Yannick; Schuchhardt, Johannes; Smit, Ines; Thiel, Christoph; Timmermann, Bernd; Verheijen, Marcha; Wittenberger, Timo; Wolski, Witold; Zerck, Alexandra; Heymans, Stephane; Kuepfer, Lars; Roth, Adrian; Schlapbach, Ralph; Niederer, Steven; Herwig, Ralf; Kleinjans, Jos.

In: Communications Biology, Vol. 3, No. 1, 573, 15.10.2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Network integration and modelling of dynamic drug responses at multi-omics levels

AU - Selevsek, Nathalie

AU - Caiment, Florian

AU - Nudischer, Ramona

AU - Gmuender, Hans

AU - Agarkova, Irina

AU - Atkinson, Francis L.

AU - Bachmann, Ivo

AU - Baier, Vanessa

AU - Barel, Gal

AU - Bauer, Chris

AU - Boerno, Stefan

AU - Bosc, Nicolas

AU - Clayton, Olivia

AU - Cordes, Henrik

AU - Deeb, Sally

AU - Gotta, Stefano

AU - Guye, Patrick

AU - Hersey, Anne

AU - Hunter, Fiona M. I.

AU - Kunz, Laura

AU - Lewalle, Alex

AU - Lienhard, Matthias

AU - Merken, Jort

AU - Minguet, Jasmine

AU - Oliveira, Bernardo

AU - Pluess, Carla

AU - Sarkans, Ugis

AU - Schrooders, Yannick

AU - Schuchhardt, Johannes

AU - Smit, Ines

AU - Thiel, Christoph

AU - Timmermann, Bernd

AU - Verheijen, Marcha

AU - Wittenberger, Timo

AU - Wolski, Witold

AU - Zerck, Alexandra

AU - Heymans, Stephane

AU - Kuepfer, Lars

AU - Roth, Adrian

AU - Schlapbach, Ralph

AU - Niederer, Steven

AU - Herwig, Ralf

AU - Kleinjans, Jos

PY - 2020/10/15

Y1 - 2020/10/15

KW - INDUCED HEART-FAILURE

KW - GENE-EXPRESSION

KW - BIOCONDUCTOR PACKAGE

KW - CLINICAL-PRACTICE

KW - CARDIOTOXICITY

KW - DOXORUBICIN

KW - SEQ

KW - CARDIOMYOPATHY

KW - MECHANISMS

KW - TOXICITY

U2 - 10.1038/s42003-020-01302-8

DO - 10.1038/s42003-020-01302-8

M3 - Article

VL - 3

JO - Communications Biology

JF - Communications Biology

SN - 2399-3642

IS - 1

M1 - 573

ER -