Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

S.A.S. Kjeldsen, L.H. Hansen, N. Esser, S. Mongovin, M. Winther-Sorensen, K.D. Galsgaard, J.E. Hunt, H. Kissow, F.R. Ceutz, D. Terzic, P.D. Mark, P. Plomgaard, J.P. Goetze, G.H. Goossens, E.E. Blaak, C.F. Deacon, M.M. Rosenkilde, S. Zraika, J.J. Holst, N.J.W. Albrechtsen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)
Original languageEnglish
Article numberbvab084
Number of pages15
JournalJournal of the endocrine society
Volume5
Issue number9
DOIs
Publication statusPublished - 1 Sep 2021

Keywords

  • Entresto (sacubitril/valsartan)
  • proglucagon-derived peptides
  • metabolism
  • ATRIAL-NATRIURETIC-PEPTIDE
  • ALPHA-CELL HYPERPLASIA
  • NEUTRAL ENDOPEPTIDASE
  • GAS-CHROMATOGRAPHY
  • SANDWICH ELISA
  • HEART-FAILURE
  • RECEPTOR
  • GLUCOSE
  • INSULIN
  • PLASMA

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