Neovascular Age-Related Macular Degeneration in the Era of Value-Based Health Care

Mari Elshout

doi:10.26481/dis.20190516me

Neovascular Age-Related Macular Degeneration in the Era of Value-Based Health Care

Mari Elshout

Research output: Thesis › Doctoral Thesis › Internal

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Abstract

Neovascular age-related macular degeneration is a disorder of the retina in the eye. The dissertation describes that without treatment, sharpness of sight and quality of life of patients deteriorate considerably. Earlier studies have investigated the cost-effectiveness of treatments, often with incorrect assumptions. A new computer model showed that treatment with the medicine ‘bevacizumab’ is cost-effective. Furthermore, the thesis describes methods that can help ophthalmologists make decisions about whether or not to treat a patient, based on the sharpness of sight and quality of life. Treatments have also been compared on practical results. Points for improvement in diagnosis and treatment were also found.

Original language	English
Awarding Institution	Maastricht University
Supervisors/Advisors	Webers, Carroll, Supervisor Schouten, Jan S. A. G., Co-Supervisor, External person
Award date	16 May 2019
Place of Publication	Maastricht
Publisher	Gildeprint Drukkerijen
Print ISBNs	9789463235556
DOIs	https://doi.org/10.26481/dis.20190516me
Publication status	Published - 2019

Keywords

Ophthalmology
retina
macular degeneration
Therapy
Cost effectiveness
Quality of life

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10.26481/dis.20190516me

Full TextFinal published version, 12.9 MB
AbstractFinal published version, 7.17 MB
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ValorisationFinal published version, 66 KB

Cite this

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abstract = "Neovascular age-related macular degeneration is a disorder of the retina in the eye. The dissertation describes that without treatment, sharpness of sight and quality of life of patients deteriorate considerably. Earlier studies have investigated the cost-effectiveness of treatments, often with incorrect assumptions. A new computer model showed that treatment with the medicine {\textquoteleft}bevacizumab{\textquoteright} is cost-effective. Furthermore, the thesis describes methods that can help ophthalmologists make decisions about whether or not to treat a patient, based on the sharpness of sight and quality of life. Treatments have also been compared on practical results. Points for improvement in diagnosis and treatment were also found.",

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AB - Neovascular age-related macular degeneration is a disorder of the retina in the eye. The dissertation describes that without treatment, sharpness of sight and quality of life of patients deteriorate considerably. Earlier studies have investigated the cost-effectiveness of treatments, often with incorrect assumptions. A new computer model showed that treatment with the medicine ‘bevacizumab’ is cost-effective. Furthermore, the thesis describes methods that can help ophthalmologists make decisions about whether or not to treat a patient, based on the sharpness of sight and quality of life. Treatments have also been compared on practical results. Points for improvement in diagnosis and treatment were also found.

KW - Ophthalmology

KW - retina

KW - macular degeneration

KW - Therapy

KW - Cost effectiveness

KW - Quality of life

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DO - 10.26481/dis.20190516me

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PB - Gildeprint Drukkerijen

CY - Maastricht

ER -

Neovascular Age-Related Macular Degeneration in the Era of Value-Based Health Care

Abstract

Keywords

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