Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers

Myriam Chalabi, Lorenzo F. Fanchi, Krijn K. Dijkstra, Jose G. van den Berg, Arend G. Aalbers, Karolina Sikorska, Marta Lopez-Yurda, Cecile Grootscholten, Geerard L. Beets, Petur Snaebjornsson, Monique Maas, Marjolijn Mertz, Vivien Veninga, Gergana Bounova, Annegien Broeks, Regina G. Beets-Tan, Thomas R. de Wijkerslooth, Anja U. van Lent, Hendrik A. Marsman, Elvira NuijtenNiels F. Kok, Maria Kuiper, Wieke H. Verbeek, Marleen Kok, Monique E. Van Leerdam, Ton N. Schumacher, Emile E. Voest, John B. Haanen

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)566-576
Number of pages25
JournalNature Medicine
Volume26
DOIs
Publication statusPublished - 2020

Keywords

  • DNA MISMATCH REPAIR
  • COLORECTAL-CANCER
  • PD-1 BLOCKADE
  • GENERATION
  • TUMORS
  • NIVOLUMAB
  • SURVIVAL
  • THERAPY
  • EVASION
  • CELLS

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