TY - JOUR
T1 - Near infrared fluorescence imaging of the urethra
T2 - a systematic review of the literature
AU - Al-Taher, Mahdi
AU - Knapen, Bob
AU - Barberio, Manuel
AU - Felli, Eric
AU - Gioux, Sylvain
AU - Bouvy, Nicole D.
AU - Stassen, Laurents P. S.
AU - Marescaux, Jacques
AU - Diana, Michele
N1 - Funding Information:
Jacques Marescaux is the President of both the IRCAD, which is partly funded by KARL STORZ and Medtronic. Laurents Stassen and Michele Diana are members of the board of Diagnostic Green (travel fees). Michele Diana is the recipient of the ELIOS grant. The remaining authors have no conflicts of interest or financial ties to disclose.
Publisher Copyright:
© 2020 Society of Medical Innovation and Technology.
PY - 2022/3/1
Y1 - 2022/3/1
N2 - Background Urethral injury is a dreaded complication during laparoscopic, perineal and transanal surgery and is mainly a result of a failed visualization of the urethra. The aim of this systematic review is to provide an overview of the available literature on the near-infrared fluorescence (NIRF) imaging technique using contrast agents for the intra-operative visualization of the urethra. Material and methods A systematic review of the literature was conducted including studies on NIRF imaging using contrast agents to visualize the urethra. All studies describing a NIRF imaging technique and demonstrating visual findings of the urethra were included. Results Five studies were identified. Four studies examined indocyanine green, one of which also studied the IRDye(R)800BK agent and one examined the CP-IRT dye. All studies showed that the NIRF imaging technique was feasible for an early identification of the urethra. No complications related to NIRF imaging were reported. Conclusion We conclude that the use of a NIRF imaging technique is feasible and that it can contribute to prevent iatrogenic injury to the urethra. However, based on the limited available data, no solid conclusion can yet be drawn and further translation to the clinical practice is necessary.
AB - Background Urethral injury is a dreaded complication during laparoscopic, perineal and transanal surgery and is mainly a result of a failed visualization of the urethra. The aim of this systematic review is to provide an overview of the available literature on the near-infrared fluorescence (NIRF) imaging technique using contrast agents for the intra-operative visualization of the urethra. Material and methods A systematic review of the literature was conducted including studies on NIRF imaging using contrast agents to visualize the urethra. All studies describing a NIRF imaging technique and demonstrating visual findings of the urethra were included. Results Five studies were identified. Four studies examined indocyanine green, one of which also studied the IRDye(R)800BK agent and one examined the CP-IRT dye. All studies showed that the NIRF imaging technique was feasible for an early identification of the urethra. No complications related to NIRF imaging were reported. Conclusion We conclude that the use of a NIRF imaging technique is feasible and that it can contribute to prevent iatrogenic injury to the urethra. However, based on the limited available data, no solid conclusion can yet be drawn and further translation to the clinical practice is necessary.
KW - Fluorescence imaging
KW - urethral visualization
KW - fluorescent dyes
KW - near-infrared
KW - total mesorectal excision
KW - TOTAL MESORECTAL EXCISION
KW - SURGERY
KW - TUMORS
U2 - 10.1080/13645706.2020.1826974
DO - 10.1080/13645706.2020.1826974
M3 - (Systematic) Review article
C2 - 33000653
SN - 1364-5706
VL - 31
SP - 342
EP - 349
JO - Minimally Invasive Therapy & Allied Technologies
JF - Minimally Invasive Therapy & Allied Technologies
IS - 3
ER -