National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

J.A. Langendijk; F.J.P. Hoebers; M.A. de Jong; P. Doornaert; C.H.J. Terhaard; R.J.H.M. Steenbakkers; O. Hamming-Vrieze; J.B. van de Kamer; W.F.A.R. Verbakel; F. Keskin-Cambay; J.B. Reitsma; A. van der Schaaf; L.J. Boersma; E. Schuit

doi:10.14338/IJPT-20-00089.1

National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

J.A. Langendijk^*
, F.J.P. Hoebers
, M.A. de Jong
, P. Doornaert
, C.H.J. Terhaard
, R.J.H.M. Steenbakkers
, O. Hamming-Vrieze
, J.B. van de Kamer
, W.F.A.R. Verbakel
, F. Keskin-Cambay
, J.B. Reitsma
, A. van der Schaaf
, L.J. Boersma
, E. Schuit

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.

Original language	English
Pages (from-to)	354-365
Number of pages	12
Journal	International Journal of Particle Therapy
Volume	8
Issue number	1
DOIs	https://doi.org/10.14338/IJPT-20-00089.1
Publication status	Published - 1 Jun 2021

Keywords

head and neck cancer
proton therapy
model-based selection
national indication protocol
radiation-induced side effects
INTENSITY-MODULATED RADIOTHERAPY
PATIENT-RATED XEROSTOMIA
3-DIMENSIONAL CONFORMAL RADIOTHERAPY
QUALITY-OF-LIFE
STICKY SALIVA
NTCP MODELS
VALIDATION
CHEMOTHERAPY
GASTROSTOMY
DELINEATION

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Langendijk, J. A., Hoebers, F. J. P., de Jong, M. A., Doornaert, P., Terhaard, C. H. J., Steenbakkers, R. J. H. M., Hamming-Vrieze, O., van de Kamer, J. B., Verbakel, W. F. A. R., Keskin-Cambay, F., Reitsma, J. B., van der Schaaf, A., Boersma, L. J., & Schuit, E. (2021). National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer. International Journal of Particle Therapy, 8(1), 354-365. https://doi.org/10.14338/IJPT-20-00089.1

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abstract = "In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.",

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Langendijk, JA, Hoebers, FJP, de Jong, MA, Doornaert, P, Terhaard, CHJ, Steenbakkers, RJHM, Hamming-Vrieze, O, van de Kamer, JB, Verbakel, WFAR, Keskin-Cambay, F, Reitsma, JB, van der Schaaf, A, Boersma, LJ & Schuit, E 2021, 'National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer', International Journal of Particle Therapy, vol. 8, no. 1, pp. 354-365. https://doi.org/10.14338/IJPT-20-00089.1

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T1 - National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

AU - Langendijk, J.A.

AU - Hoebers, F.J.P.

AU - de Jong, M.A.

AU - Doornaert, P.

AU - Terhaard, C.H.J.

AU - Steenbakkers, R.J.H.M.

AU - Hamming-Vrieze, O.

AU - van de Kamer, J.B.

AU - Verbakel, W.F.A.R.

AU - Keskin-Cambay, F.

AU - Reitsma, J.B.

AU - van der Schaaf, A.

AU - Boersma, L.J.

AU - Schuit, E.

PY - 2021/6/1

Y1 - 2021/6/1

N2 - In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.

AB - In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.

KW - head and neck cancer

KW - proton therapy

KW - model-based selection

KW - national indication protocol

KW - radiation-induced side effects

KW - INTENSITY-MODULATED RADIOTHERAPY

KW - PATIENT-RATED XEROSTOMIA

KW - 3-DIMENSIONAL CONFORMAL RADIOTHERAPY

KW - QUALITY-OF-LIFE

KW - STICKY SALIVA

KW - NTCP MODELS

KW - VALIDATION

KW - CHEMOTHERAPY

KW - GASTROSTOMY

KW - DELINEATION

U2 - 10.14338/IJPT-20-00089.1

DO - 10.14338/IJPT-20-00089.1

M3 - Article

C2 - 34285961

SN - 2331-5180

VL - 8

SP - 354

EP - 365

JO - International Journal of Particle Therapy

JF - International Journal of Particle Therapy

IS - 1

ER -

National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

Abstract

Keywords

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