Abstract
In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.
Original language | English |
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Pages (from-to) | 354-365 |
Number of pages | 12 |
Journal | International Journal of Particle Therapy |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jun 2021 |
Keywords
- head and neck cancer
- proton therapy
- model-based selection
- national indication protocol
- radiation-induced side effects
- INTENSITY-MODULATED RADIOTHERAPY
- PATIENT-RATED XEROSTOMIA
- 3-DIMENSIONAL CONFORMAL RADIOTHERAPY
- QUALITY-OF-LIFE
- STICKY SALIVA
- NTCP MODELS
- VALIDATION
- CHEMOTHERAPY
- GASTROSTOMY
- DELINEATION