Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

M. Steklov, S. Pandolf, M. F. Baietti, A. Batiuk, P. Carai, P. Najm, M. Zhang, H. Jang, F. Renzi, Y. Cai, L. Abbasi Asbagh, T. Pastor, M. De Troyer, M. Simicek, E. Radaelli, H. Brems, E. Legius, J. Tavernier, K. Gevaert, F. ImpensL. Messiaen, R. Nussinov, S. Heymans, S. Eyekerman, A. A. Sablina*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1177-1182
Number of pages6
JournalScience
Volume362
Issue number6419
DOIs
Publication statusPublished - 7 Dec 2018

Keywords

  • FAST INTERACTION REFINEMENT
  • RARE VARIANTS
  • MEMBRANE
  • FIREDOCK
  • REVEALS
  • CHARMM

Cite this

Steklov, M., Pandolf, S., Baietti, M. F., Batiuk, A., Carai, P., Najm, P., Zhang, M., Jang, H., Renzi, F., Cai, Y., Asbagh, L. A., Pastor, T., De Troyer, M., Simicek, M., Radaelli, E., Brems, H., Legius, E., Tavernier, J., Gevaert, K., ... Sablina, A. A. (2018). Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination. Science, 362(6419), 1177-1182. https://doi.org/10.1126/science.aap7607