Mutation location and I-Ks requlation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region

Peter J Schwartz*, Cristina Moreno, Maria-Christina Kotta, Matteo Pedrazzini, Lia Crotti, Federica Dagradi, Silvia Castelletti, Kristina H Haugaa, Isabelle Denjoy, Maria A Shkolnikova, Paul A Brink, Marshall J Heradien, Sandrine R M Seyen, Roel L H M G Spätjens, Carla Spazzolini, Paul G A Volders

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Web of Science)
Original languageEnglish
Pages (from-to)4743-4755
Number of pages14
JournalEuropean Heart Journal
Volume42
Issue number46
Early online date10 Sep 2021
DOIs
Publication statusPublished - 7 Dec 2021

Keywords

  • Long QT syndrome
  • Genetics
  • Sudden cardiac death
  • DOMINANT-NEGATIVE SUPPRESSION
  • LANGE-NIELSEN-SYNDROME
  • GENETIC MODIFIER
  • CHANNEL
  • KVLQT1
  • REQUIREMENT
  • MECHANISMS
  • PHENOTYPE
  • VARIANTS
  • GENOTYPE

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