Muscle Metabolic Modulation by Chronic Hypoxia

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Abstract

De Palma et al. published a research paper in which they describe the effect of chronic hypoxia on rat skeletal muscle metabolism by means of a comparative proteomic analysis (J. Proteome Res. 2007, 6(5), 1974-1984). For this, relatively young animals were used. In our communication, we note that, based on other literature, it is likely that the adaptive response of skeletal muscle to hypoxia attenuates with age. Keywords: skeletal muscles * hypoxia * muscle fiber types * energy metabolism * hypoxia inducible factor 1alpha (HIF1alpha).
Original languageEnglish
Pages (from-to)3400-3401
JournalJournal of Proteome Research
Volume6
Issue number9
DOIs
Publication statusPublished - 1 Jan 2007

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