Multiscale modeling of cardiac electrical activity

Philippe Comtois, Mark Potse, Alain Vinet*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Models of cardiac electrical activity cover a wide range of spatial scales, from the genesis of the ionic currents in individual cardiomyocytes to the generation of electrocardiograms on the torso. The level of detail that is appropriate and practicable depends on the problem investigated and the scope of the computations that are required. We briefly present three examples of modelling: the dynamics of the entrainment of a single cell, the impact of fibrosis on electrical propagation in a piece of tissue and the generation of ECG in human. In each case, the methods, results and limitations are discussed.
Original languageEnglish
Pages (from-to)57-64
JournalM S-Medecine Sciences
Issue number1
Publication statusPublished - Jan 2010

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