Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

Oana Sorop, Ilkka Heinonen, Matthijs van Kranenburg, Jens van de Wouw, Vincent J. de Beer, Isabel T. N. Nguyen, Yanti Octavia, Richard W. B. van Duin, Kelly Stam, Robert-Jan van Geuns, Piotr A. Wielopolski, Gabriel P. Krestin, Anton H. van den Meiracker, Robin Verjans, Marc van Bilsen, A. H. Jan Danser, Walter J. Paulus, Caroline Cheng, Wolfgang A. Linke, Jaap A. JolesMarianne C. Verhaar, Jolanda van der Velden, Daphne Merkus, Dirk J. Duncker

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)954-964
Number of pages11
JournalCardiovascular Research
Volume114
Issue number7
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • Translational studies
  • Coronary circulation
  • Oxidant stress
  • Endothelium/nitric oxide
  • Heart failure
  • PRESERVED EJECTION FRACTION
  • HEART-FAILURE
  • NONCARDIAC COMORBIDITIES
  • METABOLIC SYNDROME
  • PRESSURE-OVERLOAD
  • MODEL
  • INFLAMMATION
  • MECHANISMS
  • POPULATION
  • STIFFNESS

Cite this

Sorop, O., Heinonen, I., van Kranenburg, M., van de Wouw, J., de Beer, V. J., Nguyen, I. T. N., Octavia, Y., van Duin, R. W. B., Stam, K., van Geuns, R-J., Wielopolski, P. A., Krestin, G. P., van den Meiracker, A. H., Verjans, R., van Bilsen, M., Danser, A. H. J., Paulus, W. J., Cheng, C., Linke, W. A., ... Duncker, D. J. (2018). Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. Cardiovascular Research, 114(7), 954-964. https://doi.org/10.1093/cvr/cvy038