Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

Oana Sorop; Ilkka Heinonen; Matthijs van Kranenburg; Jens van de Wouw; Vincent J. de Beer; Isabel T. N. Nguyen; Yanti Octavia; Richard W. B. van Duin; Kelly Stam; Robert-Jan van Geuns; Piotr A. Wielopolski; Gabriel P. Krestin; Anton H. van den Meiracker; Robin Verjans; Marc van Bilsen; A. H. Jan Danser; Walter J. Paulus; Caroline Cheng; Wolfgang A. Linke; Jaap A. Joles; Marianne C. Verhaar; Jolanda van der Velden; Daphne Merkus; Dirk J. Duncker

doi:10.1093/cvr/cvy038

Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

Oana Sorop, Ilkka Heinonen, Matthijs van Kranenburg, Jens van de Wouw, Vincent J. de Beer, Isabel T. N. Nguyen, Yanti Octavia, Richard W. B. van Duin, Kelly Stam, Robert-Jan van Geuns, Piotr A. Wielopolski, Gabriel P. Krestin, Anton H. van den Meiracker, Robin Verjans, Marc van Bilsen, A. H. Jan Danser, Walter J. Paulus, Caroline Cheng, Wolfgang A. Linke, Jaap A. JolesMarianne C. Verhaar, Jolanda van der Velden, Daphne Merkus, Dirk J. Duncker^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

88 Citations (Web of Science)

Original language	English
Pages (from-to)	954-964
Number of pages	11
Journal	Cardiovascular Research
Volume	114
Issue number	7
DOIs	https://doi.org/10.1093/cvr/cvy038
Publication status	Published - 1 Jun 2018

Keywords

Translational studies
Coronary circulation
Oxidant stress
Endothelium/nitric oxide
Heart failure
PRESERVED EJECTION FRACTION
HEART-FAILURE
NONCARDIAC COMORBIDITIES
METABOLIC SYNDROME
PRESSURE-OVERLOAD
MODEL
INFLAMMATION
MECHANISMS
POPULATION
STIFFNESS

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10.1093/cvr/cvy038

https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvy038/23842822/cvy038.pdf

Cite this

Sorop, O., Heinonen, I., van Kranenburg, M., van de Wouw, J., de Beer, V. J., Nguyen, I. T. N., Octavia, Y., van Duin, R. W. B., Stam, K., van Geuns, R-J., Wielopolski, P. A., Krestin, G. P., van den Meiracker, A. H., Verjans, R., van Bilsen, M., Danser, A. H. J., Paulus, W. J., Cheng, C., Linke, W. A., ... Duncker, D. J. (2018). Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. Cardiovascular Research, 114(7), 954-964. https://doi.org/10.1093/cvr/cvy038

Sorop, Oana ; Heinonen, Ilkka ; van Kranenburg, Matthijs ; van de Wouw, Jens ; de Beer, Vincent J. ; Nguyen, Isabel T. N. ; Octavia, Yanti ; van Duin, Richard W. B. ; Stam, Kelly ; van Geuns, Robert-Jan ; Wielopolski, Piotr A. ; Krestin, Gabriel P. ; van den Meiracker, Anton H. ; Verjans, Robin ; van Bilsen, Marc ; Danser, A. H. Jan ; Paulus, Walter J. ; Cheng, Caroline ; Linke, Wolfgang A. ; Joles, Jaap A. ; Verhaar, Marianne C. ; van der Velden, Jolanda ; Merkus, Daphne ; Duncker, Dirk J. / Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. In: Cardiovascular Research. 2018 ; Vol. 114, No. 7. pp. 954-964.

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title = "Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening",

keywords = "Translational studies, Coronary circulation, Oxidant stress, Endothelium/nitric oxide, Heart failure, PRESERVED EJECTION FRACTION, HEART-FAILURE, NONCARDIAC COMORBIDITIES, METABOLIC SYNDROME, PRESSURE-OVERLOAD, MODEL, INFLAMMATION, MECHANISMS, POPULATION, STIFFNESS",

author = "Oana Sorop and Ilkka Heinonen and {van Kranenburg}, Matthijs and {van de Wouw}, Jens and {de Beer}, {Vincent J.} and Nguyen, {Isabel T. N.} and Yanti Octavia and {van Duin}, {Richard W. B.} and Kelly Stam and {van Geuns}, Robert-Jan and Wielopolski, {Piotr A.} and Krestin, {Gabriel P.} and {van den Meiracker}, {Anton H.} and Robin Verjans and {van Bilsen}, Marc and Danser, {A. H. Jan} and Paulus, {Walter J.} and Caroline Cheng and Linke, {Wolfgang A.} and Joles, {Jaap A.} and Verhaar, {Marianne C.} and {van der Velden}, Jolanda and Daphne Merkus and Duncker, {Dirk J.}",

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doi = "10.1093/cvr/cvy038",

language = "English",

volume = "114",

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Sorop, O, Heinonen, I, van Kranenburg, M, van de Wouw, J, de Beer, VJ, Nguyen, ITN, Octavia, Y, van Duin, RWB, Stam, K, van Geuns, R-J, Wielopolski, PA, Krestin, GP, van den Meiracker, AH, Verjans, R, van Bilsen, M, Danser, AHJ, Paulus, WJ, Cheng, C, Linke, WA, Joles, JA, Verhaar, MC, van der Velden, J, Merkus, D & Duncker, DJ 2018, 'Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening', Cardiovascular Research, vol. 114, no. 7, pp. 954-964. https://doi.org/10.1093/cvr/cvy038

Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. / Sorop, Oana; Heinonen, Ilkka; van Kranenburg, Matthijs; van de Wouw, Jens; de Beer, Vincent J.; Nguyen, Isabel T. N.; Octavia, Yanti; van Duin, Richard W. B.; Stam, Kelly; van Geuns, Robert-Jan; Wielopolski, Piotr A.; Krestin, Gabriel P.; van den Meiracker, Anton H.; Verjans, Robin; van Bilsen, Marc; Danser, A. H. Jan; Paulus, Walter J.; Cheng, Caroline; Linke, Wolfgang A.; Joles, Jaap A.; Verhaar, Marianne C.; van der Velden, Jolanda; Merkus, Daphne; Duncker, Dirk J.

In: Cardiovascular Research, Vol. 114, No. 7, 01.06.2018, p. 954-964.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

AU - Sorop, Oana

AU - Heinonen, Ilkka

AU - van Kranenburg, Matthijs

AU - van de Wouw, Jens

AU - de Beer, Vincent J.

AU - Nguyen, Isabel T. N.

AU - Octavia, Yanti

AU - van Duin, Richard W. B.

AU - Stam, Kelly

AU - van Geuns, Robert-Jan

AU - Wielopolski, Piotr A.

AU - Krestin, Gabriel P.

AU - van den Meiracker, Anton H.

AU - Verjans, Robin

AU - van Bilsen, Marc

AU - Danser, A. H. Jan

AU - Paulus, Walter J.

AU - Cheng, Caroline

AU - Linke, Wolfgang A.

AU - Joles, Jaap A.

AU - Verhaar, Marianne C.

AU - van der Velden, Jolanda

AU - Merkus, Daphne

AU - Duncker, Dirk J.

PY - 2018/6/1

Y1 - 2018/6/1

KW - Translational studies

KW - Coronary circulation

KW - Oxidant stress

KW - Endothelium/nitric oxide

KW - Heart failure

KW - PRESERVED EJECTION FRACTION

KW - HEART-FAILURE

KW - NONCARDIAC COMORBIDITIES

KW - METABOLIC SYNDROME

KW - PRESSURE-OVERLOAD

KW - MODEL

KW - INFLAMMATION

KW - MECHANISMS

KW - POPULATION

KW - STIFFNESS

U2 - 10.1093/cvr/cvy038

DO - 10.1093/cvr/cvy038

M3 - Article

C2 - 29432575

VL - 114

SP - 954

EP - 964

JO - Cardiovascular Research

JF - Cardiovascular Research

SN - 0008-6363

IS - 7

ER -