Multiphysics Finite-Element Modeling of the Neuron/Electrode Electrodiffusive Interaction

F. Leva*, C. Verardo, L.J. Mele, P. Palestri, L. Selmi

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Abstract

Understanding the biological-electrical transduction mechanisms is essential for reliable neural signal recording and feature extraction. As an alternative to state-of-the-art lumped-element circuit models, here we adopt a multiscale-multiphysics finite-element modeling framework. The model couples ion transport with the Hodgkin-Huxley model and the readout circuit, and is used to investigate a few relevant case studies. This approach is amenable to explore ion transport in the extracellular medium otherwise invisible to circuit model analysis.
Original languageEnglish
Title of host publication2022 IEEE SENSORS
PublisherIEEE
Pages1-4
Number of pages4
ISBN (Print)9781665484640
DOIs
Publication statusPublished - 2022
EventIEEE Sensors Conference - Dallas, United States
Duration: 30 Oct 20222 Nov 2022

Publication series

SeriesIEEE Sensors
ISSN1930-0395

Conference

ConferenceIEEE Sensors Conference
Country/TerritoryUnited States
CityDallas
Period30/10/222/11/22

Keywords

  • neural recording
  • extracellular sensing
  • FEM
  • neural signal transduction
  • Hodgkin-Huxley
  • EQUIVALENT-CIRCUIT
  • RECORDINGS

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