Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)

Lisa D. Geomini; Loes Janssen; Iris Hoogendoorn; Lieke Ma van Susante; Gerrit D. Slooter; Maryska Lg Janssen-Heijnen; Cochrane Colorectal Review Group

doi:10.1002/14651858.CD016381

Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)

Lisa D. Geomini
, Loes Janssen
, Iris Hoogendoorn
, Lieke Ma van Susante
, Gerrit D. Slooter
, Maryska Lg Janssen-Heijnen
, Cochrane Colorectal Review Group

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-related quality of life for people with colorectal cancer undergoing elective resection.

Original language	English
Article number	CD016381
Number of pages	13
Journal	Cochrane Database of Systematic Reviews
Volume	8
DOIs	https://doi.org/10.1002/14651858.CD016381
Publication status	Published - 18 Aug 2026

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10.1002/14651858.CD016381

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Geomini, L. D., Janssen, L., Hoogendoorn, I., van Susante, L. M., Slooter, G. D., Janssen-Heijnen, M. L., & Cochrane Colorectal Review Group (2026). Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol). Cochrane Database of Systematic Reviews, 8, Article CD016381. https://doi.org/10.1002/14651858.CD016381

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title = "Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)",

abstract = "OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-related quality of life for people with colorectal cancer undergoing elective resection.",

author = "Geomini, \{Lisa D.\} and Loes Janssen and Iris Hoogendoorn and \{van Susante\}, \{Lieke Ma\} and Slooter, \{Gerrit D.\} and Janssen-Heijnen, \{Maryska Lg\} and \{Cochrane Colorectal Review Group\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2026 The Authors. Cochrane Database of Systematic Reviews published by John Wiley \& Sons, Ltd. on behalf of The Cochrane Collaboration.",

year = "2026",

month = aug,

day = "18",

doi = "10.1002/14651858.CD016381",

language = "English",

volume = "8",

journal = "Cochrane Database of Systematic Reviews",

issn = "1469-493X",

publisher = "Wiley",

}

Geomini, LD, Janssen, L, Hoogendoorn, I, van Susante, LM, Slooter, GD, Janssen-Heijnen, ML & Cochrane Colorectal Review Group 2026, 'Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)', Cochrane Database of Systematic Reviews, vol. 8, CD016381. https://doi.org/10.1002/14651858.CD016381

Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol). / Geomini, Lisa D.; Janssen, Loes; Hoogendoorn, Iris et al.
In: Cochrane Database of Systematic Reviews, Vol. 8, CD016381, 18.08.2026.

Research output: Contribution to journal › (Systematic) Review article › peer-review

TY - JOUR

T1 - Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)

AU - Geomini, Lisa D.

AU - Janssen, Loes

AU - Hoogendoorn, Iris

AU - van Susante, Lieke Ma

AU - Slooter, Gerrit D.

AU - Janssen-Heijnen, Maryska Lg

AU - Cochrane Colorectal Review Group

PY - 2026/8/18

Y1 - 2026/8/18

N2 - OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-related quality of life for people with colorectal cancer undergoing elective resection.

AB - OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-related quality of life for people with colorectal cancer undergoing elective resection.

U2 - 10.1002/14651858.CD016381

DO - 10.1002/14651858.CD016381

M3 - (Systematic) Review article

SN - 1469-493X

VL - 8

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

M1 - CD016381

ER -

Geomini LD, Janssen L, Hoogendoorn I, van Susante LM, Slooter GD, Janssen-Heijnen ML et al. Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol). Cochrane Database of Systematic Reviews. 2026 Aug 18;8:CD016381. doi: 10.1002/14651858.CD016381

Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Protocol)

Abstract

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