Multiinstitutional study on target volume delineation variation in breast radiotherapy in the presence of guidelines

Dutch Young Boost Study Group; Liesbeth Boersma

doi:10.1016/j.radonc.2010.01.009

Multiinstitutional study on target volume delineation variation in breast radiotherapy in the presence of guidelines

Dutch Young Boost Study Group, Liesbeth Boersma

Research output: Contribution to journal › Article › Academic › peer-review

102 Citations (Web of Science)

Abstract

This study aims to determine magnitude, causes and consequences of post-operative breast tumour target volume delineation variation among radiation oncologists in the presence of guidelines.Excision cavities, CTVs and PTVs of eight breast cancer patients were delineated on CT scans by 13 Dutch radiation oncologists (observers) from 12 Dutch institutes participating in the international Young Boost Trial. Delineated volumes and conformity indices were determined. CTV delineation variation (SD) was determined for anatomically relevant regions. Non-parametric statistics were performed to establish effects of observers, patient characteristics and regions on delineation variation.Even in the presence of delineation guidelines considerable delineation variation is present (0.24

Original language	English
Pages (from-to)	286-291
Journal	Radiotherapy and Oncology
Volume	94
Issue number	3
DOIs	https://doi.org/10.1016/j.radonc.2010.01.009
Publication status	Published - Mar 2010

Keywords

Interobserver variation
Delineation
Partial breast
Clips
Guidelines
Breast cancer

Access to Document

10.1016/j.radonc.2010.01.009

Cite this

@article{e30b9d9ab34149d6833c33264e61c157,

title = "Multiinstitutional study on target volume delineation variation in breast radiotherapy in the presence of guidelines",

abstract = "This study aims to determine magnitude, causes and consequences of post-operative breast tumour target volume delineation variation among radiation oncologists in the presence of guidelines.Excision cavities, CTVs and PTVs of eight breast cancer patients were delineated on CT scans by 13 Dutch radiation oncologists (observers) from 12 Dutch institutes participating in the international Young Boost Trial. Delineated volumes and conformity indices were determined. CTV delineation variation (SD) was determined for anatomically relevant regions. Non-parametric statistics were performed to establish effects of observers, patient characteristics and regions on delineation variation.Even in the presence of delineation guidelines considerable delineation variation is present (0.24",

keywords = "Interobserver variation, Delineation, Partial breast, Clips, Guidelines, Breast cancer",

author = "{van Mourik}, {Anke M.} and Elkhuizen, {Paula H. M.} and Danny Minkema and Duppen, {Joop C.} and {Dutch Young Boost Study Group} and Liesbeth Boersma and {van Vliet-Vroegindeweij}, Corine",

year = "2010",

month = mar,

doi = "10.1016/j.radonc.2010.01.009",

language = "English",

volume = "94",

pages = "286--291",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

TY - JOUR

T1 - Multiinstitutional study on target volume delineation variation in breast radiotherapy in the presence of guidelines

AU - van Mourik, Anke M.

AU - Elkhuizen, Paula H. M.

AU - Minkema, Danny

AU - Duppen, Joop C.

AU - Dutch Young Boost Study Group

AU - Boersma, Liesbeth

AU - van Vliet-Vroegindeweij, Corine

PY - 2010/3

Y1 - 2010/3

N2 - This study aims to determine magnitude, causes and consequences of post-operative breast tumour target volume delineation variation among radiation oncologists in the presence of guidelines.Excision cavities, CTVs and PTVs of eight breast cancer patients were delineated on CT scans by 13 Dutch radiation oncologists (observers) from 12 Dutch institutes participating in the international Young Boost Trial. Delineated volumes and conformity indices were determined. CTV delineation variation (SD) was determined for anatomically relevant regions. Non-parametric statistics were performed to establish effects of observers, patient characteristics and regions on delineation variation.Even in the presence of delineation guidelines considerable delineation variation is present (0.24

AB - This study aims to determine magnitude, causes and consequences of post-operative breast tumour target volume delineation variation among radiation oncologists in the presence of guidelines.Excision cavities, CTVs and PTVs of eight breast cancer patients were delineated on CT scans by 13 Dutch radiation oncologists (observers) from 12 Dutch institutes participating in the international Young Boost Trial. Delineated volumes and conformity indices were determined. CTV delineation variation (SD) was determined for anatomically relevant regions. Non-parametric statistics were performed to establish effects of observers, patient characteristics and regions on delineation variation.Even in the presence of delineation guidelines considerable delineation variation is present (0.24

KW - Interobserver variation

KW - Delineation

KW - Partial breast

KW - Clips

KW - Guidelines

KW - Breast cancer

U2 - 10.1016/j.radonc.2010.01.009

DO - 10.1016/j.radonc.2010.01.009

M3 - Article

C2 - 20199818

VL - 94

SP - 286

EP - 291

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

SN - 0167-8140

IS - 3

ER -