TY - JOUR
T1 - Multi-Domain Screening
T2 - Identification of Patient’s Risk Profile Prior to Head-and-Neck Cancer Treatment
AU - Wieland, Monse W.M.
AU - Pilz, Walmari
AU - Winkens, Bjorn
AU - Hoeben, Ann
AU - Willemsen, Anna C.H.
AU - Kremer, Bernd
AU - Baijens, Laura W.J.
N1 - Funding Information:
This research was funded by Stichting Michel Keijzer Fonds, a non-profit fund managed by the Dutch Head and Neck Cancer Patient Support Group (Michel Keijzer Fonds|PVHH).
Publisher Copyright:
© 2023 by the authors.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - Background: Head-and-neck cancer (HNC) can give rise to oropharyngeal dysphagia (OD), malnutrition, sarcopenia, and frailty. Early identification of these phenomena in newly diagnosed HNC patients is important to reduce the risk of complications and to improve treatment outcomes. The aim of this study was (1) to determine the prevalence of the risk of OD, malnutrition, sarcopenia, and frailty; and (2) to investigate the relation between these phenomena and patients’ age, performance status, and cancer group staging. Methods: Patients (N = 128) underwent multi-domain screening consisting of the Eating Assessment Tool-10 for OD, Short Nutritional Assessment Questionnaire and BMI for malnutrition, Short Physical Performance Battery and Hand Grip Strength for sarcopenia, and Distress Thermometer and Maastricht Frailty Screening Tool for frailty. Results: 26.2%, 31.0%, 73.0%, and 46.4% of the patients were at risk for OD, malnutrition, sarcopenia, or frailty, respectively. Patients with an advanced cancer stage had a significantly higher risk of OD and high levels of distress prior to cancer treatment. Conclusions: This study identified the risk profile of newly diagnosed HNC patients using a standardized ‘quick and easy’ multi-domain screening prior to cancer treatment.
AB - Background: Head-and-neck cancer (HNC) can give rise to oropharyngeal dysphagia (OD), malnutrition, sarcopenia, and frailty. Early identification of these phenomena in newly diagnosed HNC patients is important to reduce the risk of complications and to improve treatment outcomes. The aim of this study was (1) to determine the prevalence of the risk of OD, malnutrition, sarcopenia, and frailty; and (2) to investigate the relation between these phenomena and patients’ age, performance status, and cancer group staging. Methods: Patients (N = 128) underwent multi-domain screening consisting of the Eating Assessment Tool-10 for OD, Short Nutritional Assessment Questionnaire and BMI for malnutrition, Short Physical Performance Battery and Hand Grip Strength for sarcopenia, and Distress Thermometer and Maastricht Frailty Screening Tool for frailty. Results: 26.2%, 31.0%, 73.0%, and 46.4% of the patients were at risk for OD, malnutrition, sarcopenia, or frailty, respectively. Patients with an advanced cancer stage had a significantly higher risk of OD and high levels of distress prior to cancer treatment. Conclusions: This study identified the risk profile of newly diagnosed HNC patients using a standardized ‘quick and easy’ multi-domain screening prior to cancer treatment.
KW - frailty
KW - head and neck cancer
KW - malnutrition
KW - oropharyngeal dysphagia
KW - sarcopenia
KW - screening
U2 - 10.3390/cancers15215254
DO - 10.3390/cancers15215254
M3 - Article
SN - 2072-6694
VL - 15
JO - Cancers
JF - Cancers
IS - 21
M1 - 5254
ER -