mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes

Yahya Sohrabi, Sina M. M. Lagache, Lucia Schnack, Rinesh Godfrey, Florian Kahles, Dennis Bruemmer, Johannes Waltenberger, Hannes M. Findeisen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number3155
Number of pages14
JournalFrontiers in Immunology
Volume9
DOIs
Publication statusPublished - 22 Jan 2019

Keywords

  • trained innate immunity
  • monocytes
  • mTOR
  • oxidative stress
  • HIF1 alpha
  • MACROPHAGE IMMUNOMETABOLISM
  • ACTIVATION
  • METABOLISM
  • DIPHENYLENEIODONIUM
  • ATHEROSCLEROSIS
  • ACCUMULATION
  • INFLAMMATION

Cite this

Sohrabi, Y., Lagache, S. M. M., Schnack, L., Godfrey, R., Kahles, F., Bruemmer, D., Waltenberger, J., & Findeisen, H. M. (2019). mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes. Frontiers in Immunology, 9, [3155]. https://doi.org/10.3389/fimmu.2018.03155