MRI for attenuation correction in PET: methods and challenges

G. Wagenknecht; H.J. Kaiser; F.M. Mottaghy; H. Herzog

doi:10.1007/s10334-012-0353-4

MRI for attenuation correction in PET: methods and challenges

G. Wagenknecht^*, H.J. Kaiser, F.M. Mottaghy, H. Herzog

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.

Original language	English
Pages (from-to)	99-113
Number of pages	15
Journal	Magnetic Resonance Materials in Physics Biology and Medicine
Volume	26
Issue number	1
DOIs	https://doi.org/10.1007/s10334-012-0353-4
Publication status	Published - Feb 2013

Keywords

PET/MR
MR-based attenuation correction
Brain
Whole body
Coils
Truncation artefact
WHOLE-BODY PET/MR
ULTRASHORT ECHO TIME
HYBRID PET/MRI
INHOMOGENEITY CORRECTION
DIXON TECHNIQUE
SURFACE COILS
CT IMAGES
SYSTEMS
QUANTIFICATION
SEGMENTATION

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Cite this

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title = "MRI for attenuation correction in PET: methods and challenges",

abstract = "In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.",

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author = "G. Wagenknecht and H.J. Kaiser and F.M. Mottaghy and H. Herzog",

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T1 - MRI for attenuation correction in PET: methods and challenges

AU - Wagenknecht, G.

AU - Kaiser, H.J.

AU - Mottaghy, F.M.

AU - Herzog, H.

PY - 2013/2

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N2 - In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.

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KW - PET/MR

KW - MR-based attenuation correction

KW - Brain

KW - Whole body

KW - Coils

KW - Truncation artefact

KW - WHOLE-BODY PET/MR

KW - ULTRASHORT ECHO TIME

KW - HYBRID PET/MRI

KW - INHOMOGENEITY CORRECTION

KW - DIXON TECHNIQUE

KW - SURFACE COILS

KW - CT IMAGES

KW - SYSTEMS

KW - QUANTIFICATION

KW - SEGMENTATION

U2 - 10.1007/s10334-012-0353-4

DO - 10.1007/s10334-012-0353-4

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