TY - JOUR
T1 - Movement disorder and sensorimotor abnormalities in schizophrenia and other psychoses - European consensus on assessment and perspectives
AU - Walther, Sebastian
AU - van Harten, Peter N.
AU - Waddington, John L.
AU - Cuesta, Manuel J.
AU - Peralta, Victor
AU - Dupin, Lucile
AU - Foucher, Jack R.
AU - Sambataro, Fabio
AU - Morrens, Manuel
AU - Kubera, Katharina M.
AU - Pieters, Lydia E.
AU - Stegmayer, Katharina
AU - Strik, Werner
AU - Wolf, R. Christian
AU - Hirjak, Dusan
N1 - Funding Information:
This work was supported by the German Research Foundation (DFG) (grant number DFG HI 1928/2-1 to D.H. and R.C.W.), Department of Health of the Government of Navarra (grants 11/101 and 87/2014 ) and the Carlos III Health Institute (FEDER Funds) from the Spanish Ministry of Economy and Competitivity (grants 11/02831 , 14/01621 and 16/02148 ), the Swiss National Science Foundation (grants 182469 and 184717 to S.W.) and the French Programme Hospitalier de Recherche Clinique national ( DGS 2005/0543 to J.R.F.).
Publisher Copyright:
© 2020
PY - 2020/9
Y1 - 2020/9
N2 - Over the last three decades, movement disorder as well as sensorimotor and psychomotor functioning in schizophrenia (SZ) and other psychoses has gained greater scientific and clinical relevance as an intrinsic component of the disease process of psychotic illness; this extends to early psychosis prediction, early detection of motor side effects of antipsychotic medication, clinical outcome monitoring, treatment of psychomotor syndromes (e.g. catatonia), and identification of new targets for non-invasive brain stimulation. In 2017, a systematic cooperation between working groups interested in movement disorder and sensorimotor/psychomotor functioning in psychoses was initiated across European universities. As a first step, the members of this group would like to introduce and define the theoretical aspects of the sensorimotor domain in SZ and other psychoses. This consensus paper is based on a synthesis of scientific evidence, good clinical practice and expert opinions that were discussed during recent conferences hosted by national and international psychiatric associations. While reviewing and discussing the recent theoretical and experimental work on neural mechanisms and clinical implications of sensorimotor behavior, we here seek to define the key principles and elements of research on movement disorder and sensorimotor/psychomotor functioning in psychotic illness. Finally, the members of this European group anticipate that this consensus paper will stimulate further multimodal and prospective studies on hypo- and hyperkinetic movement disorders and sensorimotor/psychomotor functioning in SZ and other psychotic disorders. (C) 2020 Elsevier B.V. and ECNP. All rights reserved.
AB - Over the last three decades, movement disorder as well as sensorimotor and psychomotor functioning in schizophrenia (SZ) and other psychoses has gained greater scientific and clinical relevance as an intrinsic component of the disease process of psychotic illness; this extends to early psychosis prediction, early detection of motor side effects of antipsychotic medication, clinical outcome monitoring, treatment of psychomotor syndromes (e.g. catatonia), and identification of new targets for non-invasive brain stimulation. In 2017, a systematic cooperation between working groups interested in movement disorder and sensorimotor/psychomotor functioning in psychoses was initiated across European universities. As a first step, the members of this group would like to introduce and define the theoretical aspects of the sensorimotor domain in SZ and other psychoses. This consensus paper is based on a synthesis of scientific evidence, good clinical practice and expert opinions that were discussed during recent conferences hosted by national and international psychiatric associations. While reviewing and discussing the recent theoretical and experimental work on neural mechanisms and clinical implications of sensorimotor behavior, we here seek to define the key principles and elements of research on movement disorder and sensorimotor/psychomotor functioning in psychotic illness. Finally, the members of this European group anticipate that this consensus paper will stimulate further multimodal and prospective studies on hypo- and hyperkinetic movement disorders and sensorimotor/psychomotor functioning in SZ and other psychotic disorders. (C) 2020 Elsevier B.V. and ECNP. All rights reserved.
KW - 1ST-EPISODE SCHIZOPHRENIA
KW - ANTIPSYCHOTIC-NAIVE PATIENTS
KW - BRAINS RESTING STATE
KW - CORTICAL INHIBITION
KW - Consensus
KW - HIGH-RISK
KW - INVOLUNTARY MOVEMENTS
KW - MOTOR ABNORMALITIES
KW - Movement disorders
KW - NEUROLOGICAL SOFT SIGNS
KW - Psychomotor
KW - Psychosis
KW - RECENT-ONSET SCHIZOPHRENIA
KW - SPATIOTEMPORAL PSYCHOPATHOLOGY
KW - Schizophrenia
KW - Sensorimotor abnormalities
KW - RATING-SCALE
U2 - 10.1016/j.euroneuro.2020.07.003
DO - 10.1016/j.euroneuro.2020.07.003
M3 - (Systematic) Review article
C2 - 32713718
SN - 0924-977X
VL - 38
SP - 25
EP - 39
JO - European Neuropsychopharmacology
JF - European Neuropsychopharmacology
ER -