Motor Disturbance in ASD: A Pilot Study Showing Hypokinetic Behavior?

M. A. L. Mostert-Kerckhoffs*, A. E. Willems, D. E. Tenback, J. P. Koning, P. Van Harten, W. G. Staal

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)
52 Downloads (Pure)

Abstract

Data supporting theoretical models linking autism spectrum disorders (ASD) to motor disturbance are inconclusive. In the present study, children and adolescents with ASD (n=44) were compared with a matched group of typically developing individuals (n=49) on both instrumental and observational assessments of motor abnormalities. No group differences were found in the instrumental data. However, more bradykinetic motor behavior was found using an observational scale in the ASD groups. More rigid motor behavior was found in the adolescents with ASD but not in the children. Individuals with ASD show significantly more hypokinetic behavior, which may not be strictly dopaminergic in origin, but may reflect a weak central coherency in neuronal networks related to the motor system in which developmental changes are present.

Original languageEnglish
Pages (from-to)415-428
Number of pages14
JournalJournal of Autism and Developmental Disorders
Volume50
Issue number2
Early online date31 Oct 2019
DOIs
Publication statusPublished - Feb 2020

Keywords

  • AUTISM
  • Autism spectrum disorder
  • CHILDREN
  • COMMUNICATION DEFICITS
  • DISORDERS
  • DRD3 GENE
  • Dyskinesia
  • FORCE VARIABILITY
  • FUNCTIONAL CONNECTIVITY
  • Motor disturbance
  • Parkinsonism
  • SKILLS
  • SPECTRUM
  • TARDIVE-DYSKINESIA
  • AUTISM SPECTRUM DISORDER
  • SCHIZOPHRENIA
  • IMPAIRMENT

Cite this