Mononuclear phagocytes in head and neck squamous cell carcinoma

Kenneth Wilfried Kross; John Helge Heimdal; Hans Jorgen Aarstad

doi:10.1007/s00405-009-1153-y

Mononuclear phagocytes in head and neck squamous cell carcinoma

Kenneth Wilfried Kross^*, John Helge Heimdal, Hans Jorgen Aarstad

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Web of Science)

Abstract

The head and neck squamous cell carcinoma microenvironments contain many immune cells and their secretory products. Many of these cells belong to the mononuclear phagocyte system. The aim of this review is to study the interactions between mononuclear phagocytes and head and neck squamous cell carcinoma tissue. The role of inflammation in tumours and the cytokine interleukin-6 will be highlighted. Future therapy strategies in the treatment of head and neck cancer might be directed towards mononuclear phagocytes and their cytokine production.

Original language	English
Pages (from-to)	335-344
Journal	European Archives of Oto-Rhino-Laryngology
Volume	267
Issue number	3
DOIs	https://doi.org/10.1007/s00405-009-1153-y
Publication status	Published - Mar 2010

Keywords

Mononuclear phagocytes
Innate immune system
Macrophages
Monocytes
Interleukin-6
Fragment spheroids
Head and neck squamous cell carcinoma

Access to Document

10.1007/s00405-009-1153-y

Cite this

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title = "Mononuclear phagocytes in head and neck squamous cell carcinoma",

abstract = "The head and neck squamous cell carcinoma microenvironments contain many immune cells and their secretory products. Many of these cells belong to the mononuclear phagocyte system. The aim of this review is to study the interactions between mononuclear phagocytes and head and neck squamous cell carcinoma tissue. The role of inflammation in tumours and the cytokine interleukin-6 will be highlighted. Future therapy strategies in the treatment of head and neck cancer might be directed towards mononuclear phagocytes and their cytokine production.",

keywords = "Mononuclear phagocytes, Innate immune system, Macrophages, Monocytes, Interleukin-6, Fragment spheroids, Head and neck squamous cell carcinoma",

author = "Kross, {Kenneth Wilfried} and Heimdal, {John Helge} and Aarstad, {Hans Jorgen}",

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T1 - Mononuclear phagocytes in head and neck squamous cell carcinoma

AU - Kross, Kenneth Wilfried

AU - Heimdal, John Helge

AU - Aarstad, Hans Jorgen

PY - 2010/3

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N2 - The head and neck squamous cell carcinoma microenvironments contain many immune cells and their secretory products. Many of these cells belong to the mononuclear phagocyte system. The aim of this review is to study the interactions between mononuclear phagocytes and head and neck squamous cell carcinoma tissue. The role of inflammation in tumours and the cytokine interleukin-6 will be highlighted. Future therapy strategies in the treatment of head and neck cancer might be directed towards mononuclear phagocytes and their cytokine production.

AB - The head and neck squamous cell carcinoma microenvironments contain many immune cells and their secretory products. Many of these cells belong to the mononuclear phagocyte system. The aim of this review is to study the interactions between mononuclear phagocytes and head and neck squamous cell carcinoma tissue. The role of inflammation in tumours and the cytokine interleukin-6 will be highlighted. Future therapy strategies in the treatment of head and neck cancer might be directed towards mononuclear phagocytes and their cytokine production.

KW - Mononuclear phagocytes

KW - Innate immune system

KW - Macrophages

KW - Monocytes

KW - Interleukin-6

KW - Fragment spheroids

KW - Head and neck squamous cell carcinoma

U2 - 10.1007/s00405-009-1153-y

DO - 10.1007/s00405-009-1153-y

M3 - Article

C2 - 19967383

VL - 267

SP - 335

EP - 344

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

SN - 0937-4477

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ER -