Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation

Paula A. da Costa Martins*

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

2 Citations (Web of Science)

Abstract

Reporting in Nature Genetics, Patterson et al. (2017) show that adult mammalian hearts possess an innate capacity to regenerate, which depends on a small population of mononuclear diploid cardiomyocytes. These cells undergo karyokinesis and cytokinesis, raising the possibility that endogenous cardiac muscle cells can be stimulated to proliferate for myocardial repair.

Original languageEnglish
Pages (from-to)421-422
Number of pages2
JournalCell Stem Cell
Volume21
Issue number4
DOIs
Publication statusPublished - 5 Oct 2017

Keywords

  • CARDIAC REGENERATION

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