TY - JOUR
T1 - Monocyte Subsets in Cardiovascular Disease
T2 - A Biomarker Perspective
AU - Hristov, Michael
AU - Weber, Christian
PY - 2024/7/6
Y1 - 2024/7/6
N2 - Endothelial dysfunctions together with a dysregulated immune response and lipid accumulation are important confounding factors in the onset and chronic development of atherosclerosis. Recently, a large body of data has emerged on the sequential involvement of different immune cell types, including monocytes, in the pathology of this disease. In this condensed review, we aim to highlight some of the recent basic research and clinical findings on monocyte subsets published since our joint European Society of Cardiology consensus document, and re-evaluate their potential relevance as surrogate biomarkers in coronary artery disease.
AB - Endothelial dysfunctions together with a dysregulated immune response and lipid accumulation are important confounding factors in the onset and chronic development of atherosclerosis. Recently, a large body of data has emerged on the sequential involvement of different immune cell types, including monocytes, in the pathology of this disease. In this condensed review, we aim to highlight some of the recent basic research and clinical findings on monocyte subsets published since our joint European Society of Cardiology consensus document, and re-evaluate their potential relevance as surrogate biomarkers in coronary artery disease.
U2 - 10.1055/a-2348-5697
DO - 10.1055/a-2348-5697
M3 - (Systematic) Review article
SN - 0340-6245
JO - Thrombosis and Haemostasis
JF - Thrombosis and Haemostasis
ER -