Monitoring neovascularization in aggressive posterior retinopathy of prematurity using optical coherence tomography angiography

Anand Vinekar*, Lavanya Chidambara, Chaitra Jayadev, Munusamy Sivakumar, Carroll A. B. Webers, Bhujang Shetty

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Web of Science)

Abstract

We describe the use of optical coherence tomography angiography (OCTA) in detecting and monitoring regression of the neovascular complex (NVC) in a case of aggressive posterior retinopathy of prematurity (AP-ROP). A premature Asian Indian girl with AP-ROP underwent laser photoablation at 26 days of life. Persistent NVC at the posterior border of the lasered retinal bed was detected clinically. On en face spectral domain optical coherence tomography (SD-OCT) and OCTA, the NVC appeared as an arborizing vascular net in the superficial capillary plexus. The deep capillary plexus and outer retinal layers showed corresponding flow outlines that suggested deeper extensions of the lesion. Supplemental laser treatment of the NVC was performed. Ten days later repeat en face SD-OCT and MA of the identical retinal location revealed that the vascular tortuosity and dilatation had reduced and that the flow lesions in the deeper layers were undetectable. Our findings in this case suggest that the NVC in AP-ROP extends beyond the superficial retina.
Original languageEnglish
Pages (from-to)271-274
JournalJournal of American Association for Pediatric Ophthalmology and Strabismus
Volume20
Issue number3
DOIs
Publication statusPublished - Jun 2016

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