Molecularly targeted therapies in cancer: a guide for the nuclear medicine physician

S. Lheureux*, C. Denoyelle, P. S. Ohashi, J. S. De Bono, F. M. Mottaghy*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

38 Citations (Web of Science)

Abstract

Molecular imaging continues to influence every aspect of cancer care including detection, diagnosis, staging and therapy response assessment. Recent advances in the understanding of cancer biology have prompted the introduction of new targeted therapy approaches. Precision medicine in oncology has led to rapid advances and novel approaches optimizing the use of imaging modalities in cancer care, research and development. This article focuses on the concept of targeted therapy in cancer and the challenges that exist for molecular imaging in cancer care.

Original languageEnglish
Pages (from-to)S41-S54
Number of pages14
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume44
DOIs
Publication statusPublished - Aug 2017

Keywords

  • targeted therapies
  • pathway
  • imaging
  • cancer
  • CELL LUNG-CANCER
  • POSITRON-EMISSION-TOMOGRAPHY
  • TYROSINE KINASE INHIBITORS
  • ADVANCED BREAST-CANCER
  • DNA-REPAIR PATHWAYS
  • CYCLIN-DEPENDENT KINASES
  • OVARIAN-CANCER
  • TRASTUZUMAB EMTANSINE
  • METASTATIC MELANOMA
  • SIGNALING PATHWAYS

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