Molecularly Imprinted Polymer-Based Sensors for the Monitoring of Antibiotic Traces and Microorganisms in Water Samples to Combat Antimicrobial Resistance

Oliver Jamieson, Xinlu Liu, Cameron Read, Jack Reeder, Toby Hallam, Kasper Eersels, Bart Van Grinsven, Elizabeth Heidrich, Divya Ottoor, Marloes Peeters*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Monitoring of antibiotic and bacterial contamination in situ in a fast and low-cost manner will be key to combatting the accelerated development of the worldwide antimicrobial resistance (AMR) crisis. Molecularly Imprinted Polymers (MIPs) are synthetic receptors that are robust and low-cost whilst rivalling the affinity of antibodies, and thus are promising recognition elements that can be used in diagnostics for environmental monitoring. In this chapter, we critically evaluate portable MIP-based sensors for measuring both antibiotics and E. coli, an important indicator for microorganism contamination, in aqueous samples. The focus will be on optical and electrical detection, which provide the highest potential for point-of-care sensing. Finally, we will discuss the future of MIP-based sensors for these compounds and what improvements are needed to bring this variety of sensor closer to widespread commercial application.
Original languageEnglish
Title of host publicationMolecularly Imprinted Polymers as Artificial Antibodies for the Environmental Health: A Step Towards Achieving the Sustainable Development Goals
PublisherSpringer
Pages143-165
Number of pages23
ISBN (Electronic)9783031589959
ISBN (Print)9783031589942
DOIs
Publication statusPublished - 1 Jan 2024

Keywords

  • Antibiotics
  • Antimicrobial resistance
  • Biomimetic sensors
  • E. coli
  • Molecularly imprinted polymers
  • Water monitoring

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