Modulation of Poultry Cecal Microbiota by a Phytogenic Blend and High Concentrations of Casein in a Validated In Vitro Cecal Chicken Alimentary Tract Model

Igor V Popov*, Nouhaila Belkassem, Ruud Schrijver, Iuliia P Chebotareva, Michael L Chikindas, Alexey M Ermakov, Koen Venema

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Phytogenic blends (PBs) consist of various bioactive plant-derived compounds that are used as growth promoters for farm animals. Feed additives based on PBs have beneficial effects on farm animals’ production performance, health, and overall well-being, as well as positive modulating effects on gut microbiota. In this study, we used a validated in vitro cecal chicken alimentary tract model (CALIMERO-2) to evaluate the effects of a PB (a mix of components found in rosemary, cinnamon, curcuma, oregano oil, and red pepper), alone or in combination with casein (control), on poultry cecal microbiota. Supplementation with the PB significantly increased the abundance of bacteria associated with energy metabolism (Monoglobus) and growth performance in poultry (Lachnospiraceae UCG-010). The PB also decreased the abundance of opportunistic pathogens (Escherichia-Shigella) and, most importantly, did not promote other opportunistic pathogens, which indicates the safety of this blend for poultry. In conclusion, the results of this study show promising perspectives on using PBs as feed additives for poultry, although further in vivo studies need to prove these data.

Original languageEnglish
Article number377
JournalVeterinary Sciences
Volume11
Issue number8
DOIs
Publication statusPublished - 16 Aug 2024

Keywords

  • 16S rRNA
  • CALIMERO-2
  • in vitro cecal model
  • phytogenic blends
  • poultry

Fingerprint

Dive into the research topics of 'Modulation of Poultry Cecal Microbiota by a Phytogenic Blend and High Concentrations of Casein in a Validated In Vitro Cecal Chicken Alimentary Tract Model'. Together they form a unique fingerprint.

Cite this