Modern MR Imaging Technology in Rectal Cancer; There Is More Than Meets the Eye

Hester E. Haak*, Monique Maas, Stefano Trebeschi, Regina G. H. Beets-Tan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Citations (Web of Science)

Abstract

MR imaging (MRI) is now part of the standard work up of patients with rectal cancer. Restaging MRI has been traditionally used to plan the surgical approach. Its role has recently increased and been adopted as a valuable tool to assist the clinical selection of clinical (near) complete responders for organ preserving treatment. Recently several studies have addressed new imaging biomarkers that combined with morphological provides a comprehensive picture of the tumor. Diffusion-weighted MRI (DWI) has entered the clinics and proven useful for response assessment after chemoradiotherapy. Other functional (quantitative) MRI technologies are on the horizon including artificial intelligence modeling. This narrative review provides an overview of recent advances in rectal cancer (re)staging by imaging with a specific focus on response prediction and evaluation of neoadjuvant treatment response. Furthermore, directions are given for future research.

Original languageEnglish
Article number537532
Number of pages7
JournalFrontiers in Oncology
Volume10
DOIs
Publication statusPublished - 8 Oct 2020

Keywords

  • rectal cancer
  • MR imaging
  • organ preservation
  • functional imaging
  • artificial intelligence
  • PATHOLOGICAL COMPLETE RESPONSE
  • APPARENT DIFFUSION-COEFFICIENT
  • NEOADJUVANT CHEMORADIOTHERAPY
  • RADIATION-THERAPY
  • PREOPERATIVE CHEMORADIATION
  • TUMOR RESPONSE
  • PREDICTING RESPONSE
  • TEXTURE ANALYSIS
  • WEIGHTED MRI
  • DCE-MRI

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