Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis

Kirsten van de Groep*, Martine P. Bos, Meri R. J. Varkila, Paul H. M. Savelkoul, David S. Y. Ong, Lennie P. G. Derde, Nicole P. Juffermans, Tom van der Poll, Marc J. M. Bonten, Olaf L. Cremer, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Arie J. Hoogendijk, Roosmarijn T. M. van Hooijdonk, Janneke Horn, Mischa A. Huson, Nicole P. Juffermans, Tom van der Poll, Laura R. A. SchoutenBrendon Scicluna, Marcus J. Schultz, Marleen Straat, Lonneke A. van Vught, Luuk Wieske, Maryse A. Wiewel, Esther Witteveen, Marc J. M. Bonten, Olaf L. Cremer, Jos F. Frencken, Peter M. C. Klein Klouwenberg, Maria E. Koster-Brouwer, David S. Y. Ong, Meri R. J. Varkila, Diana M. Verboom, MARS Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1829-1836
Number of pages8
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Volume38
Issue number10
DOIs
Publication statusPublished - Oct 2019

Keywords

  • Diagnostic research
  • Pathogen detection
  • Sepsis
  • Intensive care
  • Multiplex real-time PCR
  • INFECTIONS

Cite this

van de Groep, K., Bos, M. P., Varkila, M. R. J., Savelkoul, P. H. M., Ong, D. S. Y., Derde, L. P. G., Juffermans, N. P., van der Poll, T., Bonten, M. J. M., Cremer, O. L., de Beer, F. M., Bos, L. D. J., Glas, G. J., Hoogendijk, A. J., van Hooijdonk, R. T. M., Horn, J., Huson, M. A., Juffermans, N. P., van der Poll, T., ... MARS Consortium (2019). Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis. European Journal of Clinical Microbiology & Infectious Diseases, 38(10), 1829-1836. https://doi.org/10.1007/s10096-019-03616-w