Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis

, Kirsten van de Groep*, Martine P. Bos, Meri R. J. Varkila, Paul H. M. Savelkoul, David S. Y. Ong, Lennie P. G. Derde, Nicole P. Juffermans, Tom van der Poll, Marc J. M. Bonten, Olaf L. Cremer, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Arie J. Hoogendijk, Roosmarijn T. M. van Hooijdonk, Janneke Horn, Mischa A. Huson, Nicole P. Juffermans, Tom van der PollLaura R. A. Schouten, Brendon Scicluna, Marcus J. Schultz, Marleen Straat, Lonneke A. van Vught, Luuk Wieske, Maryse A. Wiewel, Esther Witteveen, Marc J. M. Bonten, Olaf L. Cremer, Jos F. Frencken, Peter M. C. Klein Klouwenberg, Maria E. Koster-Brouwer, David S. Y. Ong, Meri R. J. Varkila, Diana M. Verboom

*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original languageEnglish
Pages (from-to)1829-1836
Number of pages8
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Volume38
Issue number10
DOIs
Publication statusPublished - Oct 2019

Keywords

  • Diagnostic research
  • Pathogen detection
  • Sepsis
  • Intensive care
  • Multiplex real-time PCR
  • INFECTIONS

Cite this

van de Groep, Kirsten ; Bos, Martine P. ; Varkila, Meri R. J. ; Savelkoul, Paul H. M. ; Ong, David S. Y. ; Derde, Lennie P. G. ; Juffermans, Nicole P. ; van der Poll, Tom ; Bonten, Marc J. M. ; Cremer, Olaf L. ; de Beer, Friso M. ; Bos, Lieuwe D. J. ; Glas, Gerie J. ; Hoogendijk, Arie J. ; van Hooijdonk, Roosmarijn T. M. ; Horn, Janneke ; Huson, Mischa A. ; Juffermans, Nicole P. ; van der Poll, Tom ; Schouten, Laura R. A. ; Scicluna, Brendon ; Schultz, Marcus J. ; Straat, Marleen ; van Vught, Lonneke A. ; Wieske, Luuk ; Wiewel, Maryse A. ; Witteveen, Esther ; Bonten, Marc J. M. ; Cremer, Olaf L. ; Frencken, Jos F. ; Klouwenberg, Peter M. C. Klein ; Koster-Brouwer, Maria E. ; Ong, David S. Y. ; Varkila, Meri R. J. ; Verboom, Diana M. / Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis. In: European Journal of Clinical Microbiology & Infectious Diseases. 2019 ; Vol. 38, No. 10. pp. 1829-1836.
@article{5674b0b8ea7b4164aed1dcf24c1b3179,
title = "Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis",
keywords = "Diagnostic research, Pathogen detection, Sepsis, Intensive care, Multiplex real-time PCR, INFECTIONS",
author = "{van de Groep}, Kirsten and Bos, {Martine P.} and Varkila, {Meri R. J.} and Savelkoul, {Paul H. M.} and Ong, {David S. Y.} and Derde, {Lennie P. G.} and Juffermans, {Nicole P.} and {van der Poll}, Tom and Bonten, {Marc J. M.} and Cremer, {Olaf L.} and {de Beer}, {Friso M.} and Bos, {Lieuwe D. J.} and Glas, {Gerie J.} and Hoogendijk, {Arie J.} and {van Hooijdonk}, {Roosmarijn T. M.} and Janneke Horn and Huson, {Mischa A.} and Juffermans, {Nicole P.} and {van der Poll}, Tom and Schouten, {Laura R. A.} and Brendon Scicluna and Schultz, {Marcus J.} and Marleen Straat and {van Vught}, {Lonneke A.} and Luuk Wieske and Wiewel, {Maryse A.} and Esther Witteveen and Bonten, {Marc J. M.} and Cremer, {Olaf L.} and Frencken, {Jos F.} and Klouwenberg, {Peter M. C. Klein} and Koster-Brouwer, {Maria E.} and Ong, {David S. Y.} and Varkila, {Meri R. J.} and Verboom, {Diana M.}",
year = "2019",
month = "10",
doi = "10.1007/s10096-019-03616-w",
language = "English",
volume = "38",
pages = "1829--1836",
journal = "European Journal of Clinical Microbiology & Infectious Diseases",
issn = "0934-9723",
publisher = "Springer, Cham",
number = "10",

}

van de Groep, K, Bos, MP, Varkila, MRJ, Savelkoul, PHM, Ong, DSY, Derde, LPG, Juffermans, NP, van der Poll, T, Bonten, MJM, Cremer, OL, de Beer, FM, Bos, LDJ, Glas, GJ, Hoogendijk, AJ, van Hooijdonk, RTM, Horn, J, Huson, MA, Juffermans, NP, van der Poll, T, Schouten, LRA, Scicluna, B, Schultz, MJ, Straat, M, van Vught, LA, Wieske, L, Wiewel, MA, Witteveen, E, Bonten, MJM, Cremer, OL, Frencken, JF, Klouwenberg, PMCK, Koster-Brouwer, ME, Ong, DSY & Varkila, MRJ & Verboom, DM 2019, 'Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis', European Journal of Clinical Microbiology & Infectious Diseases, vol. 38, no. 10, pp. 1829-1836. https://doi.org/10.1007/s10096-019-03616-w

Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis. /; van de Groep, Kirsten; Bos, Martine P.; Varkila, Meri R. J.; Savelkoul, Paul H. M.; Ong, David S. Y.; Derde, Lennie P. G.; Juffermans, Nicole P.; van der Poll, Tom; Bonten, Marc J. M.; Cremer, Olaf L.; de Beer, Friso M.; Bos, Lieuwe D. J.; Glas, Gerie J.; Hoogendijk, Arie J.; van Hooijdonk, Roosmarijn T. M.; Horn, Janneke; Huson, Mischa A.; Juffermans, Nicole P.; van der Poll, Tom; Schouten, Laura R. A.; Scicluna, Brendon; Schultz, Marcus J.; Straat, Marleen; van Vught, Lonneke A.; Wieske, Luuk; Wiewel, Maryse A.; Witteveen, Esther; Bonten, Marc J. M.; Cremer, Olaf L.; Frencken, Jos F.; Klouwenberg, Peter M. C. Klein; Koster-Brouwer, Maria E.; Ong, David S. Y.; Varkila, Meri R. J.; Verboom, Diana M.

In: European Journal of Clinical Microbiology & Infectious Diseases, Vol. 38, No. 10, 10.2019, p. 1829-1836.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis

AU - van de Groep, Kirsten

AU - Bos, Martine P.

AU - Varkila, Meri R. J.

AU - Savelkoul, Paul H. M.

AU - Ong, David S. Y.

AU - Derde, Lennie P. G.

AU - Juffermans, Nicole P.

AU - van der Poll, Tom

AU - Bonten, Marc J. M.

AU - Cremer, Olaf L.

AU - de Beer, Friso M.

AU - Bos, Lieuwe D. J.

AU - Glas, Gerie J.

AU - Hoogendijk, Arie J.

AU - van Hooijdonk, Roosmarijn T. M.

AU - Horn, Janneke

AU - Huson, Mischa A.

AU - Juffermans, Nicole P.

AU - van der Poll, Tom

AU - Schouten, Laura R. A.

AU - Scicluna, Brendon

AU - Schultz, Marcus J.

AU - Straat, Marleen

AU - van Vught, Lonneke A.

AU - Wieske, Luuk

AU - Wiewel, Maryse A.

AU - Witteveen, Esther

AU - Bonten, Marc J. M.

AU - Cremer, Olaf L.

AU - Frencken, Jos F.

AU - Klouwenberg, Peter M. C. Klein

AU - Koster-Brouwer, Maria E.

AU - Ong, David S. Y.

AU - Varkila, Meri R. J.

AU - Verboom, Diana M.

PY - 2019/10

Y1 - 2019/10

KW - Diagnostic research

KW - Pathogen detection

KW - Sepsis

KW - Intensive care

KW - Multiplex real-time PCR

KW - INFECTIONS

U2 - 10.1007/s10096-019-03616-w

DO - 10.1007/s10096-019-03616-w

M3 - Article

VL - 38

SP - 1829

EP - 1836

JO - European Journal of Clinical Microbiology & Infectious Diseases

JF - European Journal of Clinical Microbiology & Infectious Diseases

SN - 0934-9723

IS - 10

ER -

van de Groep K, Bos MP, Varkila MRJ, Savelkoul PHM, Ong DSY et al. Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis. European Journal of Clinical Microbiology & Infectious Diseases. 2019 Oct;38(10):1829-1836. https://doi.org/10.1007/s10096-019-03616-w

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