Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis

Kirsten van de Groep*, Martine P. Bos, Meri R. J. Varkila, Paul H. M. Savelkoul, David S. Y. Ong, Lennie P. G. Derde, Nicole P. Juffermans, Marc J. M. Bonten, Olaf L. Cremer, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Arie J. Hoogendijk, Roosmarijn T. M. van Hooijdonk, Janneke Horn, Mischa A. Huson, Tom van der Poll, Laura R. A. Schouten, Brendon Scicluna, Marcus J. SchultzMarleen Straat, Lonneke A. van Vught, Luuk Wieske, Maryse A. Wiewel, Esther Witteveen, Jos F. Frencken, Peter M. C. Klein Klouwenberg, Maria E. Koster-Brouwer, Meri R. J. Varkila, Diana M. Verboom, MARS Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1829-1836
Number of pages8
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Issue number10
Publication statusPublished - Oct 2019


  • Diagnostic research
  • Pathogen detection
  • Sepsis
  • Intensive care
  • Multiplex real-time PCR

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