Moderate Correlations of in vitro versus in vivo Pharmacokinetics Questioning the Need of Early Microsomal Stability Testing

Eva Schrezenmeier, Frank S. Zollmann, Kerstin Seidel, Christian Boehm, Kristin Schmerbach, Melanie Kroh, Sebastian Kirsch, Sabrina Klare, Sarah Bernhard, Kai Kappert, Petra Goldin-Lang, Werner Skuballa, Thomas Unger, Heiko Funke-Kaiser*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)307-315
Issue number5-6
Publication statusPublished - 2012


  • (Pro)renin receptor
  • Drug discovery
  • Correlation
  • Microsomal stability
  • In vivo pharmacokinetics
  • High-throughput screening

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