Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation

M. Ibrahim-Kosta; P. Suchon; F. Couturaud; D. Smadja; R. Olaso; M. Germain; N. Saut; L. Goumidi; C. Derbois; F. Thibord; S. Debette; P. Amouyel; J. F. Deleuze; P. van Doorn; E. Castoldi; E. Patin; M. C. Alessi; D. A. Tregouet; P. E. Morange

doi:10.1038/s41598-019-40172-x

Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation

M. Ibrahim-Kosta, P. Suchon, F. Couturaud, D. Smadja, R. Olaso, M. Germain, N. Saut, L. Goumidi, C. Derbois, F. Thibord, S. Debette, P. Amouyel, J. F. Deleuze, P. van Doorn, E. Castoldi, E. Patin, M. C. Alessi, D. A. Tregouet, P. E. Morange^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	3750
Number of pages	7
Journal	Scientific Reports
Volume	9
DOIs	https://doi.org/10.1038/s41598-019-40172-x
Publication status	Published - 6 Mar 2019

Keywords

GENOME-WIDE ASSOCIATION
COAGULATION-FACTOR-V
B-DOMAIN
GENE
RESISTANCE
PATHWAY
RISK
DEFECTS

Access to Document

10.1038/s41598-019-40172-x

Cite this

Ibrahim-Kosta, M., Suchon, P., Couturaud, F., Smadja, D., Olaso, R., Germain, M., Saut, N., Goumidi, L., Derbois, C., Thibord, F., Debette, S., Amouyel, P., Deleuze, J. F., van Doorn, P., Castoldi, E., Patin, E., Alessi, M. C., Tregouet, D. A., & Morange, P. E. (2019). Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation. Scientific Reports, 9, [3750]. https://doi.org/10.1038/s41598-019-40172-x

Ibrahim-Kosta, M. ; Suchon, P. ; Couturaud, F. ; Smadja, D. ; Olaso, R. ; Germain, M. ; Saut, N. ; Goumidi, L. ; Derbois, C. ; Thibord, F. ; Debette, S. ; Amouyel, P. ; Deleuze, J. F. ; van Doorn, P. ; Castoldi, E. ; Patin, E. ; Alessi, M. C. ; Tregouet, D. A. ; Morange, P. E. / Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation. In: Scientific Reports. 2019 ; Vol. 9.

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title = "Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation",

keywords = "GENOME-WIDE ASSOCIATION, COAGULATION-FACTOR-V, B-DOMAIN, GENE, RESISTANCE, PATHWAY, RISK, DEFECTS",

author = "M. Ibrahim-Kosta and P. Suchon and F. Couturaud and D. Smadja and R. Olaso and M. Germain and N. Saut and L. Goumidi and C. Derbois and F. Thibord and S. Debette and P. Amouyel and Deleuze, {J. F.} and {van Doorn}, P. and E. Castoldi and E. Patin and Alessi, {M. C.} and Tregouet, {D. A.} and Morange, {P. E.}",

year = "2019",

month = mar,

day = "6",

doi = "10.1038/s41598-019-40172-x",

language = "English",

volume = "9",

journal = "Scientific Reports",

issn = "2045-2322",

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Ibrahim-Kosta, M, Suchon, P, Couturaud, F, Smadja, D, Olaso, R, Germain, M, Saut, N, Goumidi, L, Derbois, C, Thibord, F, Debette, S, Amouyel, P, Deleuze, JF, van Doorn, P, Castoldi, E, Patin, E, Alessi, MC, Tregouet, DA & Morange, PE 2019, 'Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation', Scientific Reports, vol. 9, 3750. https://doi.org/10.1038/s41598-019-40172-x

Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation. / Ibrahim-Kosta, M.; Suchon, P.; Couturaud, F.; Smadja, D.; Olaso, R.; Germain, M.; Saut, N.; Goumidi, L.; Derbois, C.; Thibord, F.; Debette, S.; Amouyel, P.; Deleuze, J. F.; van Doorn, P.; Castoldi, E.; Patin, E.; Alessi, M. C.; Tregouet, D. A.; Morange, P. E.

In: Scientific Reports, Vol. 9, 3750, 06.03.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation

AU - Ibrahim-Kosta, M.

AU - Suchon, P.

AU - Couturaud, F.

AU - Smadja, D.

AU - Olaso, R.

AU - Germain, M.

AU - Saut, N.

AU - Goumidi, L.

AU - Derbois, C.

AU - Thibord, F.

AU - Debette, S.

AU - Amouyel, P.

AU - Deleuze, J. F.

AU - van Doorn, P.

AU - Castoldi, E.

AU - Patin, E.

AU - Alessi, M. C.

AU - Tregouet, D. A.

AU - Morange, P. E.

PY - 2019/3/6

Y1 - 2019/3/6

KW - GENOME-WIDE ASSOCIATION

KW - COAGULATION-FACTOR-V

KW - B-DOMAIN

KW - GENE

KW - RESISTANCE

KW - PATHWAY

KW - RISK

KW - DEFECTS

U2 - 10.1038/s41598-019-40172-x

DO - 10.1038/s41598-019-40172-x

M3 - Article

C2 - 30842582

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 3750

ER -