Minimally invasive maxillofacial vertical bone augmentation using brushite based cements

Faleh Tamimi*, Jesus Torres, Enrique Lopez-Cabarcos, David C. Bassett, Pamela Habibovic, Elena Luceron, Jake E. Barralet

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

An ideal material for maxillofacial vertical bone augmentation procedures should not only be osteo-conductive, biocompatible and mechanically strong, but should also be applied using minimally invasive procedures and remain stable with respect to the original bone surfaces. This way, implant exposure and infection might be reduced and good mechanical stability may be achieved. Calcium phosphate cements are proven biocompatible and osteoconductive materials that can be injected using minimally invasive procedures. Among these cements, brushite based cements have the added advantage of being biodegradable in vivo. Therefore, this material has the potential for use in the aforementioned procedures. An in vivo study was performed in rabbits to evaluate the potential use of brushite cements in minimally invasive maxillofacial vertical bone augmentation procedures. In this study, we injected self-setting brushite cements on the subperiosteal bone surface using a minimally invasive tunnelling technique. The cement pastes were stable on the boric surface and hardened soon after they were injected thereby negating the need for additional supports such as membranes or meshes. The animals were sacrificed 8 weeks after the intervention and histological observations revealed signs of successful vertical bone augmentation. Therefore, we have demonstrated a minimally invasive vertical bone augmentation procedure that is an attractive alternative to current surgical procedures in terms of increased simplicity, reduced trauma, and lower cost of surgery. (c) 2008 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)208-216
Number of pages9
JournalBiomaterials
Volume30
Issue number2
DOIs
Publication statusPublished - Jan 2009
Externally publishedYes

Keywords

  • Bone cement
  • Brushite
  • Minimal invasive surgery
  • Injectable biomaterials
  • Vertical bone augmentation
  • Biocompatibility
  • ALVEOLAR RIDGE AUGMENTATION
  • BETA-TRICALCIUM PHOSPHATE
  • DISTRACTION OSTEOGENESIS
  • BIOLOGICAL-PROPERTIES
  • HYDRAULIC CEMENT
  • HYDROXYLAPATITE
  • GRAFTS
  • RESORPTION
  • PH
  • RECONSTRUCTION

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