Miniaturised eight-channel impedance spectroscopy unit as sensor platform for biosensor applications

Jeroen Broeders*, Stijn Duchateau, Bart Van Grinsven, Wouter Vanaken, Marloes Peeters, Thomas Cleij, Ronald Thoelen, Patrick Wagner, Ward De Ceuninck

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Web of Science)

Abstract

A miniaturised, low cost impedance analyser is developed to ease the use of impedance spectroscopy in biological setups. This could form the first step towards fully standalone, hand-held biosensor applications. The system is capable of performing quasi-simultaneous time resolved impedance measurements on eight different channels in a frequency range of 10 hz–100 khz. The unit is accurate in a broad impedance range and is able to perform stable measurements over intervals of several days. The system is characterised by passive components, a temperature controlled wet cell based impedance setup and a biomimetic molecularly imprinted polymer (mip) based histamine sensor. The test results all indicate accurate and stable functioning of the unit, making it suitable for bioanalytical applications.
Original languageEnglish
Pages (from-to)1357-1363
JournalPhysica Status Solidi A-applications and Materials Science
Volume208
Issue number6
DOIs
Publication statusPublished - Jun 2011
Externally publishedYes

Keywords

  • biosensors
  • electrochemical analysis
  • impedance spectroscopy
  • molecular imprinting

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