Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Sara Botschuijver, Sophie A. van Diest, Isabelle A. M. van Thiel, Rafael S. Saia, Anne S. Strik, Zhumei Yu, Daniele Maria-Ferreira, Olaf Welting, Daniel Keszthelyi, Gary Jennings, Sigrid E. M. Heinsbroek, Ronald P. Oude Elferink, Frank H. J. Schuren, Wouter J. de Jonge, Rene M. van den Wijngaard*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number12530
Number of pages11
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 29 Aug 2019

Keywords

  • TRIGEMINAL SENSORY NEURONS
  • IN-VITRO
  • LIPID RAFTS
  • MAST-CELLS
  • TRPV1
  • ACTIVATION
  • SENSITIVITY
  • DISRUPTION
  • SYMPTOMS
  • EFFICACY

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