Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices

Bjorn Harink, Severine Le Gac, David Barata, Clemens van Blitterswijk, Pamela Habibovic*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

We present a microtiter plate-sized standalone chip holder for precise control of physiological conditions inside closed microfluidic cell culture systems, made from gas-impermeable materials. Specifically, we demonstrate the suitability of the holder to support cell growth in a glass chip, to allow time-lapse imaging of live cells and the creation of a hypoxic environment, all relevant for applications in regenerative medicine research.
Original languageEnglish
Pages (from-to)1816-1820
JournalLab on A Chip
Volume14
Issue number11
DOIs
Publication statusPublished - 2014

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