Microbiota profiling in gastrointestinal health and disease: (special focus on methodological and analytical approaches)

Danyta Isthylova Tedjo

doi:10.26481/dis.20180301dt

Microbiota profiling in gastrointestinal health and disease: (special focus on methodological and analytical approaches)

Danyta Isthylova Tedjo

Research output: Thesis › Doctoral Thesis › Internal

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Abstract

This dissertation examines the role of intestinal microbiota (gut microbiota) in Crohn's disease, liver cirrhosis and obesity. The results show that microbiota composition in patients with Crohn's disease, morbid obesity and liver cirrhosis is different than the microbiota of healthy individuals and that these changes play a role in the severity of the disease. It can be concluded that determining the microbiota composition may be used in the future in the diagnosis and prognosis of these diseases.

Original language	English
Awarding Institution	Maastricht University
Supervisors/Advisors	Masclee, Ad, Supervisor Savelkoul, Paul, Supervisor Jonkers, Daisy, Co-Supervisor Penders, John, Co-Supervisor
Award date	1 Mar 2018
Place of Publication	Maastricht
Publisher	Ridderprint
Print ISBNs	9789462998582
DOIs	https://doi.org/10.26481/dis.20180301dt
Publication status	Published - 2018

Keywords

microbiota
Crohn's disease
liver cirrhosis
obesity

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10.26481/dis.20180301dt

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Cite this

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abstract = "This dissertation examines the role of intestinal microbiota (gut microbiota) in Crohn's disease, liver cirrhosis and obesity. The results show that microbiota composition in patients with Crohn's disease, morbid obesity and liver cirrhosis is different than the microbiota of healthy individuals and that these changes play a role in the severity of the disease. It can be concluded that determining the microbiota composition may be used in the future in the diagnosis and prognosis of these diseases.",

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AB - This dissertation examines the role of intestinal microbiota (gut microbiota) in Crohn's disease, liver cirrhosis and obesity. The results show that microbiota composition in patients with Crohn's disease, morbid obesity and liver cirrhosis is different than the microbiota of healthy individuals and that these changes play a role in the severity of the disease. It can be concluded that determining the microbiota composition may be used in the future in the diagnosis and prognosis of these diseases.

KW - microbiota

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KW - liver cirrhosis

KW - obesity

U2 - 10.26481/dis.20180301dt

DO - 10.26481/dis.20180301dt

M3 - Doctoral Thesis

SN - 9789462998582

PB - Ridderprint

CY - Maastricht

ER -

Microbiota profiling in gastrointestinal health and disease: (special focus on methodological and analytical approaches)

Abstract

Keywords

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