Methodological aspects of deep brain stimulation: the untold story behind DBS surgery

Today, surgical instruments and technologies provide countless important advantages for surgical teams during DBS electrode implantation. However, in order to have successful results with DBS therapy, all these technologies and instruments must be used in harmony. In this study, the methodological aspects of DBS (Deep Brain Stimulation) surgery technique were reported, investigated and questioned. Stereotactic frames, stereotactic localizers, stereotactic planning stations, radiological imaging systems, neurophysiological recording systems, pros and cons of these technologies were reported and discussed through five different studies. In addition to the retrospective qualitative analysis of experienced technical events and complications, potential scenarios were designed and the effects of these scenarios on surgical instruments and systems were investigated. Moreover, pros and cons of MER (Microelectrode Recording) methodology in DBS surgeries were discussed and presented with respect to our perspective and approach to DBS therapy.