Metformin-associated lactic acidosis in a patient with normal kidney function.

T.T. van Sloten; E. Pijpers; C.D.A. Stehouwer; M.C. Brouwers

doi:10.1016/j.diabres.2011.07.021

Metformin-associated lactic acidosis in a patient with normal kidney function.

T.T. van Sloten
, E. Pijpers
, C.D.A. Stehouwer
, M.C. Brouwers^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Abstract

The existence of metformin-induced lactic acidosis has been questioned, in particular in the absence of specific risk factors such as impaired renal function. This report describes the presence of lactic acidosis in a patient with normal kidney function and normal doses of metformin. Subsequent positive rechallenge with metformin confirms causality.

Original language	English
Pages (from-to)	E57-E58
Number of pages	2
Journal	Diabetes Research and Clinical Practice
Volume	96
Issue number	3
DOIs	https://doi.org/10.1016/j.diabres.2011.07.021
Publication status	Published - Jun 2012

Keywords

Metformin
Biguanides
Treatment type 2 diabetes

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10.1016/j.diabres.2011.07.021

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title = "Metformin-associated lactic acidosis in a patient with normal kidney function.",

abstract = "The existence of metformin-induced lactic acidosis has been questioned, in particular in the absence of specific risk factors such as impaired renal function. This report describes the presence of lactic acidosis in a patient with normal kidney function and normal doses of metformin. Subsequent positive rechallenge with metformin confirms causality.",

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year = "2012",

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language = "English",

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AU - van Sloten, T.T.

AU - Pijpers, E.

AU - Stehouwer, C.D.A.

AU - Brouwers, M.C.

PY - 2012/6

Y1 - 2012/6

N2 - The existence of metformin-induced lactic acidosis has been questioned, in particular in the absence of specific risk factors such as impaired renal function. This report describes the presence of lactic acidosis in a patient with normal kidney function and normal doses of metformin. Subsequent positive rechallenge with metformin confirms causality.

AB - The existence of metformin-induced lactic acidosis has been questioned, in particular in the absence of specific risk factors such as impaired renal function. This report describes the presence of lactic acidosis in a patient with normal kidney function and normal doses of metformin. Subsequent positive rechallenge with metformin confirms causality.

KW - Metformin

KW - Biguanides

KW - Treatment type 2 diabetes

U2 - 10.1016/j.diabres.2011.07.021

DO - 10.1016/j.diabres.2011.07.021

M3 - Comment/Letter to the editor

C2 - 21839535

SN - 0168-8227

VL - 96

SP - E57-E58

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

IS - 3

ER -

Metformin-associated lactic acidosis in a patient with normal kidney function.

Abstract

Keywords

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