Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease

Roberta Ricciarelli, Chiara Brullo, Jos Prickaerts, Ottavio Arancio, Carla Villa, Claudia Rebosio, Elisa Calcagno, Matilde Balbi, Britt T. J. van Hagen, Elentina K. Argyrousi, Hong Zhang, Maria Adelaide Pronzato, Olga Bruno, Ernesto Fedele*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number46320
Number of pages14
JournalScientific Reports
Volume7
DOIs
Publication statusPublished - 12 Apr 2017

Keywords

  • LONG-TERM POTENTIATION
  • PROTEIN-KINASE-A
  • HIPPOCAMPAL SYNAPTIC PLASTICITY
  • LATE-PHASE
  • PHOSPHODIESTERASE 4D
  • COGNITION ENHANCEMENT
  • RECOGNITION MEMORY
  • ADENYLYL-CYCLASE
  • IMPROVES MEMORY
  • SPATIAL MEMORY

Cite this

Ricciarelli, R., Brullo, C., Prickaerts, J., Arancio, O., Villa, C., Rebosio, C., Calcagno, E., Balbi, M., van Hagen, B. T. J., Argyrousi, E. K., Zhang, H., Pronzato, M. A., Bruno, O., & Fedele, E. (2017). Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. Scientific Reports, 7, [46320]. https://doi.org/10.1038/srep46320