Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease

Roberta Ricciarelli, Chiara Brullo, Jos Prickaerts, Ottavio Arancio, Carla Villa, Claudia Rebosio, Elisa Calcagno, Matilde Balbi, Britt T. J. van Hagen, Elentina K. Argyrousi, Hong Zhang, Maria Adelaide Pronzato, Olga Bruno, Ernesto Fedele*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number46320
Number of pages14
JournalScientific Reports
Volume7
DOIs
Publication statusPublished - 12 Apr 2017

Keywords

  • LONG-TERM POTENTIATION
  • PROTEIN-KINASE-A
  • HIPPOCAMPAL SYNAPTIC PLASTICITY
  • LATE-PHASE
  • PHOSPHODIESTERASE 4D
  • COGNITION ENHANCEMENT
  • RECOGNITION MEMORY
  • ADENYLYL-CYCLASE
  • IMPROVES MEMORY
  • SPATIAL MEMORY

Cite this

Ricciarelli, Roberta ; Brullo, Chiara ; Prickaerts, Jos ; Arancio, Ottavio ; Villa, Carla ; Rebosio, Claudia ; Calcagno, Elisa ; Balbi, Matilde ; van Hagen, Britt T. J. ; Argyrousi, Elentina K. ; Zhang, Hong ; Pronzato, Maria Adelaide ; Bruno, Olga ; Fedele, Ernesto. / Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. In: Scientific Reports. 2017 ; Vol. 7.
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title = "Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease",
keywords = "LONG-TERM POTENTIATION, PROTEIN-KINASE-A, HIPPOCAMPAL SYNAPTIC PLASTICITY, LATE-PHASE, PHOSPHODIESTERASE 4D, COGNITION ENHANCEMENT, RECOGNITION MEMORY, ADENYLYL-CYCLASE, IMPROVES MEMORY, SPATIAL MEMORY",
author = "Roberta Ricciarelli and Chiara Brullo and Jos Prickaerts and Ottavio Arancio and Carla Villa and Claudia Rebosio and Elisa Calcagno and Matilde Balbi and {van Hagen}, {Britt T. J.} and Argyrousi, {Elentina K.} and Hong Zhang and Pronzato, {Maria Adelaide} and Olga Bruno and Ernesto Fedele",
year = "2017",
month = "4",
day = "12",
doi = "10.1038/srep46320",
language = "English",
volume = "7",
journal = "Scientific Reports",
issn = "2045-2322",
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}

Ricciarelli, R, Brullo, C, Prickaerts, J, Arancio, O, Villa, C, Rebosio, C, Calcagno, E, Balbi, M, van Hagen, BTJ, Argyrousi, EK, Zhang, H, Pronzato, MA, Bruno, O & Fedele, E 2017, 'Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease', Scientific Reports, vol. 7, 46320. https://doi.org/10.1038/srep46320

Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. / Ricciarelli, Roberta; Brullo, Chiara; Prickaerts, Jos; Arancio, Ottavio; Villa, Carla; Rebosio, Claudia; Calcagno, Elisa; Balbi, Matilde; van Hagen, Britt T. J.; Argyrousi, Elentina K.; Zhang, Hong; Pronzato, Maria Adelaide; Bruno, Olga; Fedele, Ernesto.

In: Scientific Reports, Vol. 7, 46320, 12.04.2017.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease

AU - Ricciarelli, Roberta

AU - Brullo, Chiara

AU - Prickaerts, Jos

AU - Arancio, Ottavio

AU - Villa, Carla

AU - Rebosio, Claudia

AU - Calcagno, Elisa

AU - Balbi, Matilde

AU - van Hagen, Britt T. J.

AU - Argyrousi, Elentina K.

AU - Zhang, Hong

AU - Pronzato, Maria Adelaide

AU - Bruno, Olga

AU - Fedele, Ernesto

PY - 2017/4/12

Y1 - 2017/4/12

KW - LONG-TERM POTENTIATION

KW - PROTEIN-KINASE-A

KW - HIPPOCAMPAL SYNAPTIC PLASTICITY

KW - LATE-PHASE

KW - PHOSPHODIESTERASE 4D

KW - COGNITION ENHANCEMENT

KW - RECOGNITION MEMORY

KW - ADENYLYL-CYCLASE

KW - IMPROVES MEMORY

KW - SPATIAL MEMORY

U2 - 10.1038/srep46320

DO - 10.1038/srep46320

M3 - Article

VL - 7

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 46320

ER -