Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

Steven Vermeulen, Nadia Roumans, Floris Honig, Aurélie Carlier, Dennie G A J Hebels, Aysegul Dede Eren, Peter Ten Dijke, Aliaksei Vasilevich, Jan de Boer*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

96 Downloads (Pure)
Original languageEnglish
Article number120331
Number of pages14
JournalBiomaterials
Volume259
DOIs
Publication statusPublished - Nov 2020

Keywords

  • Actin dynamics
  • Biomaterials
  • Mesenchymal stem cells
  • Scleraxis
  • Mechanobiology
  • TGF-beta
  • GROWTH-FACTOR-BETA
  • SERUM RESPONSE FACTOR
  • SMOOTH-MUSCLE ACTIN
  • PROTEIN-KINASE-C
  • BONE MORPHOGENETIC PROTEIN-2
  • TENOGENIC DIFFERENTIATION
  • GENE-EXPRESSION
  • MECHANICAL FORCE
  • MATRIX-STIFFNESS
  • MYOSIN-II

Cite this